PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c4gxwA_

Fold library id	PDB Header	Molecule	Title
c4gxwA_	PDB header: hydrolase	Chain: A: PDB Molecule: adenosine deaminase;	PDBTitle: crystal structure of a cog1816 amidohydrolase (target efi-505188) from2 burkhoderia ambifaria, with bound zn

Links to external resources
Added to library: Sat Sep 15 14:44:07 2012

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence G T P G N V P A A R T G I E I T A A H R A F F H A L P K V E L H C H L L G A V R H D T F V A L A Q R S G A P I E R A E I D A F Y A R G E K P

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
G G G
S
S
B B G G G
T
S
T T
S S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence V G V L H V L R A L D R Y L L T R P D D L R R I A Y E Y L E D A A A H N V R H A E F F W N P T G T V R V S G I P Y A D A Q A A I V T G M R D

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S T
S T T T
T T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence A A R D F G I G A R L I P S I D R E Q D P D E A V A I V D W M K A N R A D E V A G I G I D Y R E N D R P P E L F W K A Y R D A R A A G F R T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T S
T
T T B
S
T T
G G G G T T

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280

Sequence T A H A G E F G M P W R N V E T A V D L L H V D R V D H G Y T I V D N P E L C A R Y A E R G I V F T V V P T N S Y Y L R T L P P D Q W A E R

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
T T
T S
S
G G G G G
T
T T
S
T T T

. . . . . . . . . 290 . . . . . . . . . 300 . . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350

Sequence H P M R K M P G L G L K I H P N T D D P T L H K V N P S E A W E L M F S H F G F T I A D L K Q F M L N G I D G A W V D D D T K A A W R A A W

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
G G G G T G G G T
B S T
T S
S S S

. . . . . . . . . 360 . . . . . . . . .

Sequence A P E F D M L A D T L A A D K L A A A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	G	T	P	G	N	V	P	A	A	R	T	G	I	E	I	T	A	A	H	R	A	F	F	H	A	L	P	K	V	E	L	H	C	H	L	L	G	A	V	R	H	D	T	F	V	A	L	A	Q	R	S	G	A	P	I	E	R	A	E	I	D	A	F	Y	A	R	G	E	K	P
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			G	G	G						S															S							B	B	G	G	G															T		S			T	T										S	S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	V	G	V	L	H	V	L	R	A	L	D	R	Y	L	L	T	R	P	D	D	L	R	R	I	A	Y	E	Y	L	E	D	A	A	A	H	N	V	R	H	A	E	F	F	W	N	P	T	G	T	V	R	V	S	G	I	P	Y	A	D	A	Q	A	A	I	V	T	G	M	R	D
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			S											T			S																	T	T	T																T	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	A	A	R	D	F	G	I	G	A	R	L	I	P	S	I	D	R	E	Q	D	P	D	E	A	V	A	I	V	D	W	M	K	A	N	R	A	D	E	V	A	G	I	G	I	D	Y	R	E	N	D	R	P	P	E	L	F	W	K	A	Y	R	D	A	R	A	A	G	F	R	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																	T	T	S															T			T	T	B							S			T	T			G	G	G	G										T	T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Sequence	T	A	H	A	G	E	F	G	M	P	W	R	N	V	E	T	A	V	D	L	L	H	V	D	R	V	D	H	G	Y	T	I	V	D	N	P	E	L	C	A	R	Y	A	E	R	G	I	V	F	T	V	V	P	T	N	S	Y	Y	L	R	T	L	P	P	D	Q	W	A	E	R
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)					S		T	T												T	S			S						G	G	G	G	G												T							T	T								S		T	T	T
	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
Sequence	H	P	M	R	K	M	P	G	L	G	L	K	I	H	P	N	T	D	D	P	T	L	H	K	V	N	P	S	E	A	W	E	L	M	F	S	H	F	G	F	T	I	A	D	L	K	Q	F	M	L	N	G	I	D	G	A	W	V	D	D	D	T	K	A	A	W	R	A	A	W
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		G	G	G	G	T	G	G	G	T								B	S					T													T	S																		S	S	S
	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.
Sequence	A	P	E	F	D	M	L	A	D	T	L	A	A	D	K	L	A	A	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)