PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c4gnkE_

Fold library id	PDB Header	Molecule	Title
c4gnkE_	PDB header: gtp-binding protein/hydrolase	Chain: E: PDB Molecule: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase	PDBTitle: crystal structure of galphaq in complex with full-length human2 plcbeta3

Links to external resources
Added to library: Sat Feb 9 15:49:13 2013

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence S P G Q R D D L I A S I L S E V A P T P L D E L R G H K A L V K L R S R Q E R D L R E L R K K H Q R K A V T L T R R L L D G L A Q A Q A E G

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
G G G S
G G G G G G

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence R C R L R D E A K R Y Q E F Q N R Q V Q S L L E L R E A Q V D A E A Q R R L E H L R Q A L Q R L R E V V L D A N T T Q F K R L K E M N E R E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T T T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence K K E L Q K I L D R K R H N S I S H K K E A E L T E I N R R H I T E S V N S I R R L E E A Q K Q R H D R L V A G Q Q Q V L Q Q L A E E E P K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
T T T T T T

. . . . . . . . . 220 . . . . . . . . . 230 . . . . .

Sequence L L A Q L A Q E C Q E Q R A R L P Q E I R R S L L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T T G G G T

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	S	P	G	Q	R	D	D	L	I	A	S	I	L	S	E	V	A	P	T	P	L	D	E	L	R	G	H	K	A	L	V	K	L	R	S	R	Q	E	R	D	L	R	E	L	R	K	K	H	Q	R	K	A	V	T	L	T	R	R	L	L	D	G	L	A	Q	A	Q	A	E	G
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		G	G	G									S								G	G	G	G	G	G
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	R	C	R	L	R	D	E	A	K	R	Y	Q	E	F	Q	N	R	Q	V	Q	S	L	L	E	L	R	E	A	Q	V	D	A	E	A	Q	R	R	L	E	H	L	R	Q	A	L	Q	R	L	R	E	V	V	L	D	A	N	T	T	Q	F	K	R	L	K	E	M	N	E	R	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)							T																																																												T	T	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	K	K	E	L	Q	K	I	L	D	R	K	R	H	N	S	I	S	H	K	K	E	A	E	L	T	E	I	N	R	R	H	I	T	E	S	V	N	S	I	R	R	L	E	E	A	Q	K	Q	R	H	D	R	L	V	A	G	Q	Q	Q	V	L	Q	Q	L	A	E	E	E	P	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)															S				T	T	T	T	T																									T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.
Sequence	L	L	A	Q	L	A	Q	E	C	Q	E	Q	R	A	R	L	P	Q	E	I	R	R	S	L	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																T	T	T	T	G	G	G	T