PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c4fmoA_

Fold library id	PDB Header	Molecule	Title
c4fmoA_	PDB header: hydrolase	Chain: A: PDB Molecule: dna mismatch repair protein mlh1;	PDBTitle: structure of the c-terminal domain of the saccharomyces cerevisiae2 mutl alpha (mlh1/pms1) heterodimer bound to a fragment of exo1

Links to external resources
Added to library: Sat Feb 23 08:46:28 2013

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence R V N V N L T S I K K L R E K V D D S I H R E L T D I F A N L N Y V G V V D E E R R L A A I Q H D L K L F L I D Y G S V C Y E L F Y Q I G L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) -
B
T
T T T T T T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence T D F A N F G K I N L Q S T N V S D D I V L Y N L L S E F D E L N D D A S K E K I I S K I W D M S S M L N E Y Y S I E L V N D G L D N D L K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
S
G G G
B T T
T T S
S T
S S
T T
G G

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence S V K L K S L P L L L K G Y I P S L V K L P F F I Y R L G K E V D W E D E Q E C L D G I L R E I A L L Y I P D M V P K V D T S D A S L S E D

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) G
S T T
S T T T S
T T S S
T T
T T S

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . .

Sequence E K A Q F I N R K E H I S S L L E H V L F P C I K R R F L A P R H I L K D V V E I A N L P D L Y K V F E R C

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
B G G G G G G T T T S

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	R	V	N	V	N	L	T	S	I	K	K	L	R	E	K	V	D	D	S	I	H	R	E	L	T	D	I	F	A	N	L	N	Y	V	G	V	V	D	E	E	R	R	L	A	A	I	Q	H	D	L	K	L	F	L	I	D	Y	G	S	V	C	Y	E	L	F	Y	Q	I	G	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	-																			B										T									T	T	T	T							T	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	T	D	F	A	N	F	G	K	I	N	L	Q	S	T	N	V	S	D	D	I	V	L	Y	N	L	L	S	E	F	D	E	L	N	D	D	A	S	K	E	K	I	I	S	K	I	W	D	M	S	S	M	L	N	E	Y	Y	S	I	E	L	V	N	D	G	L	D	N	D	L	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			T	T										S		G	G	G			B						T	T		T	T	S		S														T															S	S		T	T		G	G
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	S	V	K	L	K	S	L	P	L	L	L	K	G	Y	I	P	S	L	V	K	L	P	F	F	I	Y	R	L	G	K	E	V	D	W	E	D	E	Q	E	C	L	D	G	I	L	R	E	I	A	L	L	Y	I	P	D	M	V	P	K	V	D	T	S	D	A	S	L	S	E	D
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	G										S	T	T					S	T	T											T	S		T	T	S																	S									T	T		T	T	S
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.
Sequence	E	K	A	Q	F	I	N	R	K	E	H	I	S	S	L	L	E	H	V	L	F	P	C	I	K	R	R	F	L	A	P	R	H	I	L	K	D	V	V	E	I	A	N	L	P	D	L	Y	K	V	F	E	R	C
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																			T												B	G	G	G	G	G	G											T	T	T	S