PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c4ff5A_

Fold library id	PDB Header	Molecule	Title
c4ff5A_	PDB header: hydrolase	Chain: A: PDB Molecule: glycosyl hydrolase 25;	PDBTitle: structure basis of a novel virulence factor ghip a glycosyl hydrolase2 25 of streptococcus pneumoniae participating in host cell invasion

Links to external resources
Added to library: Sat Jul 20 08:38:51 2013

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence N I A Q I E A Q A L K H L D K P I I D L S G W Q R P E E I N Y D A L S Q N I S G A I V R V H S G T T K E N D A S F I N G I D K A Y K S H I T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T T S
T T S
G G G
S
S
S
S S B
T T S B B S S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence E L Q K R N V P V A V Y A Y V A G K S V Q E M E K A A E V F Y N A A S P Y S P S Y Y W L D V E D K T M S N M N E G V E N F R A K L A S L G A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T
S S G G G
S
S
S S S T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence K N I G I Y V G V Y F M E E H S I D T G K F T S V W I P S Y G S D S G F L E S S P K T D L D Y D I H Q Y T S K G K I A G F D H D L D I N V I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
T T S S
T T
S S
S S
S
S
T T
S

. . . . . . . . . 220 . . . . . . .

Sequence S P L K N K E E T F R K L F L K P

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T S
S

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	N	I	A	Q	I	E	A	Q	A	L	K	H	L	D	K	P	I	I	D	L	S	G	W	Q	R	P	E	E	I	N	Y	D	A	L	S	Q	N	I	S	G	A	I	V	R	V	H	S	G	T	T	K	E	N	D	A	S	F	I	N	G	I	D	K	A	Y	K	S	H	I	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)												T	T	T	S							T	T	S		G	G	G									S		S												S			S	S	B		T	T	S	B	B	S	S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	E	L	Q	K	R	N	V	P	V	A	V	Y	A	Y	V	A	G	K	S	V	Q	E	M	E	K	A	A	E	V	F	Y	N	A	A	S	P	Y	S	P	S	Y	Y	W	L	D	V	E	D	K	T	M	S	N	M	N	E	G	V	E	N	F	R	A	K	L	A	S	L	G	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				T	T	T												S	S																G	G	G			S								S			S	S	S																T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	K	N	I	G	I	Y	V	G	V	Y	F	M	E	E	H	S	I	D	T	G	K	F	T	S	V	W	I	P	S	Y	G	S	D	S	G	F	L	E	S	S	P	K	T	D	L	D	Y	D	I	H	Q	Y	T	S	K	G	K	I	A	G	F	D	H	D	L	D	I	N	V	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)															T	T				T	T	S	S								T	T			S	S						S	S		S			S											T	T			S
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.
Sequence	S	P	L	K	N	K	E	E	T	F	R	K	L	F	L	K	P
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		T	T	S											S