PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c4es6A_

Fold library id	PDB Header	Molecule	Title
c4es6A_	PDB header: lyase	Chain: A: PDB Molecule: uroporphyrinogen-iii synthase;	PDBTitle: crystal structure of hemd (pa5259) from pseudomonas aeruginosa (pao1)2 at 2.22 a resolution

Links to external resources
Added to library: Mon Jan 14 11:33:15 2013

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence G W R L L L T R P D E E C A A L A A S L G E A G V H S S S L P L L A I D P L E E T P E Q R T L M L D L D R Y C A V V V V S K P A A R L G L E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
T T
S
T G G G
S
S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence R L D R Y W P Q P P Q Q T W C S V G A A T A A I L E A Y G L D V T Y P E Q G D D S E A L L A L P A F Q D S L R V H D P K V L I M R G E G G R

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S
S
S S T
S S
S T
T
S S S
S S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence E F L A E R L R G Q G V Q V D Y L P L Y R R R A P D Y P A G E L L A R V R A E R L N G L V V S S G Q G L Q N L Y Q L A A A D W P E I G R L P

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
T T T T
S G G G T T S

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . .

Sequence L F V P S P R V A E M A R E L G A Q R V I D C R G A S A P A L L A A L T S A A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S T T
S S
S S S S

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	G	W	R	L	L	L	T	R	P	D	E	E	C	A	A	L	A	A	S	L	G	E	A	G	V	H	S	S	S	L	P	L	L	A	I	D	P	L	E	E	T	P	E	Q	R	T	L	M	L	D	L	D	R	Y	C	A	V	V	V	V	S	K	P	A	A	R	L	G	L	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)								S															T	T								S																		T	G	G	G		S						S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	R	L	D	R	Y	W	P	Q	P	P	Q	Q	T	W	C	S	V	G	A	A	T	A	A	I	L	E	A	Y	G	L	D	V	T	Y	P	E	Q	G	D	D	S	E	A	L	L	A	L	P	A	F	Q	D	S	L	R	V	H	D	P	K	V	L	I	M	R	G	E	G	G	R
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)							S	S			S						S	S											T							S	S			S						T								T		S	S	S									S	S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	E	F	L	A	E	R	L	R	G	Q	G	V	Q	V	D	Y	L	P	L	Y	R	R	R	A	P	D	Y	P	A	G	E	L	L	A	R	V	R	A	E	R	L	N	G	L	V	V	S	S	G	Q	G	L	Q	N	L	Y	Q	L	A	A	A	D	W	P	E	I	G	R	L	P
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)										T	T																		T	T									T	T								S												G	G	G					T	T	S
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.
Sequence	L	F	V	P	S	P	R	V	A	E	M	A	R	E	L	G	A	Q	R	V	I	D	C	R	G	A	S	A	P	A	L	L	A	A	L	T	S	A	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				S	S										T	T		S	S					S	S	S	S