PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c4en2M_

Fold library id	PDB Header	Molecule	Title
c4en2M_	PDB header: viral protein/immune system	Chain: M: PDB Molecule: ap-1 complex subunit mu-1;	PDBTitle: hiv-1 nef in complex with mhc-i cytoplasmic domain and mu1 adaptin2 subunit of ap1 adaptor (second domain)

Links to external resources
Added to library: Sat Jun 23 13:11:18 2012

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence S W R S E G I K Y R K N E V F L D V I E A V N L L V S A N G N V L R S E I V G S I K M R V F L S G M P E L R L G L N D K V L F D N T G R G K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
S S
T T S
S
B T T
T T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence S K S V E L E D V K F H Q C V R L S R F E N D R T I S F I P P D G E F E L M S Y R L N T H V K P L I W I E S V I E K H S H S R I E Y M V K A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
B
T T B
S
S T T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence K S Q F K R R S T A N N V E I H I P V P N D A D S P K F K T T V G S V K W V P E N S E I V W S V K S F P G G K E Y L M R A H F G L K P P I S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
T T
T T
S S S T T T T S S

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . .

Sequence V K F E I P Y F T T S G I Q V R Y L K I I E K S G Y Q A L P W V R Y I T Q N G D Y Q L R T Q

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
S S
S S
S S

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	S	W	R	S	E	G	I	K	Y	R	K	N	E	V	F	L	D	V	I	E	A	V	N	L	L	V	S	A	N	G	N	V	L	R	S	E	I	V	G	S	I	K	M	R	V	F	L	S	G	M	P	E	L	R	L	G	L	N	D	K	V	L	F	D	N	T	G	R	G	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)					T	T				S	S																	T	T	S																			S										B							T	T		T	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	S	K	S	V	E	L	E	D	V	K	F	H	Q	C	V	R	L	S	R	F	E	N	D	R	T	I	S	F	I	P	P	D	G	E	F	E	L	M	S	Y	R	L	N	T	H	V	K	P	L	I	W	I	E	S	V	I	E	K	H	S	H	S	R	I	E	Y	M	V	K	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S			B									T	T	B																	S																	S												T	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	K	S	Q	F	K	R	R	S	T	A	N	N	V	E	I	H	I	P	V	P	N	D	A	D	S	P	K	F	K	T	T	V	G	S	V	K	W	V	P	E	N	S	E	I	V	W	S	V	K	S	F	P	G	G	K	E	Y	L	M	R	A	H	F	G	L	K	P	P	I	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				S		T	T														T	T									S	S	S						T	T	T	T											S	S
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.
Sequence	V	K	F	E	I	P	Y	F	T	T	S	G	I	Q	V	R	Y	L	K	I	I	E	K	S	G	Y	Q	A	L	P	W	V	R	Y	I	T	Q	N	G	D	Y	Q	L	R	T	Q
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)							S			S	S												S	S															S	S