PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c4egeA_

Fold library id	PDB Header	Molecule	Title
c4egeA_	PDB header: hydrolase	Chain: A: PDB Molecule: dipeptidase pepe;	PDBTitle: crystal structure of dipeptidase pepe from mycobacterium ulcerans

Links to external resources
Added to library: Sat Apr 28 13:35:52 2012

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence G R F D T A V Y A R R L A A A A A A T E Q A G L A G L V I T P G Y D L R Y L I G S R A D T F E R L T A L V L P A S G V P T I V L P R L E L A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
S
S S
S S S
S S S
G G G G G

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence S L K E S A A S D L G V C V R D W V D G D D P Y Q L V A V A L G G A P A A T A V T D S M P A L H L L P L A D A L G V L P V L A T D V L R Q L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) G G G T S S T T T T T
T T S
T T S S S
T T
T S
S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence R M V K E A A E V D A L A K A G A A I D R V H A R V P A F L V P G R T E A Q V A A D I A E A I V A E G H S A V A F V I V G S G P H G A D P H

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T B
T T
B T T
S G G G G G
T T

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280

Sequence H G Y S D R K L Q V G D I V V V D I G G T Y E P G Y Y S D S T R T Y S I G D P S P D V A Q Q Y S A L Q R A Q R A A V D A V R P G V T A A Q V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
B
T T
T T T
S
T T
B

. . . . . . . . . 290 . . . . . . . . . 300 . . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350

Sequence D A A A R D V L A D A G L A E Y F V H R T G H G I G L C V H E E P Y I V A G N E L P L V A G M A F S I E P G I Y F P G R W G A R I E D I V V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
G G G
S
S
S S S S S
T T
B
T T B
T T T
B

. . . . . . . . . 360 . . . . . . . . . 370 .

Sequence V T E N G A L S V N N R P H E L M V V P V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T S
S
S

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	G	R	F	D	T	A	V	Y	A	R	R	L	A	A	A	A	A	A	T	E	Q	A	G	L	A	G	L	V	I	T	P	G	Y	D	L	R	Y	L	I	G	S	R	A	D	T	F	E	R	L	T	A	L	V	L	P	A	S	G	V	P	T	I	V	L	P	R	L	E	L	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																						T	T		S						S	S														S	S	S								S	S	S								G	G	G	G	G
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	S	L	K	E	S	A	A	S	D	L	G	V	C	V	R	D	W	V	D	G	D	D	P	Y	Q	L	V	A	V	A	L	G	G	A	P	A	A	T	A	V	T	D	S	M	P	A	L	H	L	L	P	L	A	D	A	L	G	V	L	P	V	L	A	T	D	V	L	R	Q	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	G	G	G	T	S	S	T	T	T	T	T								T	T	S										T	T	S	S	S							T	T														T	S					S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	R	M	V	K	E	A	A	E	V	D	A	L	A	K	A	G	A	A	I	D	R	V	H	A	R	V	P	A	F	L	V	P	G	R	T	E	A	Q	V	A	A	D	I	A	E	A	I	V	A	E	G	H	S	A	V	A	F	V	I	V	G	S	G	P	H	G	A	D	P	H
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		T	B																													T	T		B															T	T		S										G	G	G	G	G		T	T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Sequence	H	G	Y	S	D	R	K	L	Q	V	G	D	I	V	V	V	D	I	G	G	T	Y	E	P	G	Y	Y	S	D	S	T	R	T	Y	S	I	G	D	P	S	P	D	V	A	Q	Q	Y	S	A	L	Q	R	A	Q	R	A	A	V	D	A	V	R	P	G	V	T	A	A	Q	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)					S		B			T	T												T	T	T												S																										T	T		B
	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
Sequence	D	A	A	A	R	D	V	L	A	D	A	G	L	A	E	Y	F	V	H	R	T	G	H	G	I	G	L	C	V	H	E	E	P	Y	I	V	A	G	N	E	L	P	L	V	A	G	M	A	F	S	I	E	P	G	I	Y	F	P	G	R	W	G	A	R	I	E	D	I	V	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)											T	T		G	G	G			S		S					S	S	S	S	S							T	T				B			T	T	B											T	T	T						B
	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.
Sequence	V	T	E	N	G	A	L	S	V	N	N	R	P	H	E	L	M	V	V	P	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			T	T					S			S			S