PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c4cqmJ_

Fold library id	PDB Header	Molecule	Title
c4cqmJ_	PDB header: oxidoreductase	Chain: J: PDB Molecule: carbonyl reductase family member 4;	PDBTitle: crystal structure of heterotetrameric human ketoacyl2 reductase complexed with nad and nadp

Links to external resources
Added to library: Sat Sep 13 08:51:26 2014

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence H H H M D K V C A V F G G S R G I G R A V A Q L M A R K G Y R L A V I A R N L E G A K A A A G D L G G D H L A F S C D V A K E H D V Q N T F

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T
S S T T T
S
T T
S S
T T S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence E E L E K H L G R V N F L V N A A G I N R D G L L V R T K T E D M V S Q L H T N L L G S M L T C K A A M R T M I Q Q Q G G S I V N V G S I V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
B
G G G
T T T T
S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence G L K G N S G Q S V Y S A S K G G L V G F S R A L A K E V A R K K I R V N V V A P G F V H T D M T K D L K E E H L K K N I P L G R F G E T I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T B G G G T
S B S S S T T S S S
T T S T T S S
B

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240

Sequence E V A H A V V F L L E S P Y I T G H V L V V D G G L Q L I L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
T T
S
S S S G G G T

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	H	H	H	M	D	K	V	C	A	V	F	G	G	S	R	G	I	G	R	A	V	A	Q	L	M	A	R	K	G	Y	R	L	A	V	I	A	R	N	L	E	G	A	K	A	A	A	G	D	L	G	G	D	H	L	A	F	S	C	D	V	A	K	E	H	D	V	Q	N	T	F
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)												T		S	S	T												T	T								S											T	T		S	S								T	T	S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	E	E	L	E	K	H	L	G	R	V	N	F	L	V	N	A	A	G	I	N	R	D	G	L	L	V	R	T	K	T	E	D	M	V	S	Q	L	H	T	N	L	L	G	S	M	L	T	C	K	A	A	M	R	T	M	I	Q	Q	Q	G	G	S	I	V	N	V	G	S	I	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																							B		G	G	G														T																T	T	T										S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	G	L	K	G	N	S	G	Q	S	V	Y	S	A	S	K	G	G	L	V	G	F	S	R	A	L	A	K	E	V	A	R	K	K	I	R	V	N	V	V	A	P	G	F	V	H	T	D	M	T	K	D	L	K	E	E	H	L	K	K	N	I	P	L	G	R	F	G	E	T	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						T	T	B																						G	G	G	T										S	B	S	S	S	T	T	S	S	S							T	T	S	T	T	S	S		B
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence	E	V	A	H	A	V	V	F	L	L	E	S	P	Y	I	T	G	H	V	L	V	V	D	G	G	L	Q	L	I	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)											T		T	T			S						S	S	S	G	G	G	T