PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c4b8cH_

Fold library id	PDB Header	Molecule	Title
c4b8cH_	PDB header: hydrolase/cell cycle	Chain: H: PDB Molecule: general negative regulator of transcription subunit 1;	PDBTitle: nuclease module of the yeast ccr4-not complex

Links to external resources
Added to library: Wed Jan 9 17:57:38 2013

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence Q E M I P L K F F A V D E V S C Q I N Q E G A P K D V V E K V L F V L N N V T L A N L N N K V D E L K K S L T P N Y F S W F S T Y L V T Q R

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
B
S S B
S
T T T
G G G T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence A K T E P N Y H D L Y S K V I V A M G S G L L H Q F M V N V T L R Q L F V L L S T K D E Q A I D K K H L K N L A S W L G C I T L A L N K P I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T
G G G T
B S
G G G S
T G G G T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence K H K N I A F R E M L I E A Y K E N R L E I V V P F V T K I L Q R A S E S K I F K P P N P W T V G I L K L L I E L N E K A N W K L S L T F E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T T B
T
T T G G G
T T T S T T
T

. . . . . . . . . 220 . . . . . . . . . 230 . . .

Sequence V E V L L K S F N L T T K S L K P S N F I N T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
T T S S
S

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	Q	E	M	I	P	L	K	F	F	A	V	D	E	V	S	C	Q	I	N	Q	E	G	A	P	K	D	V	V	E	K	V	L	F	V	L	N	N	V	T	L	A	N	L	N	N	K	V	D	E	L	K	K	S	L	T	P	N	Y	F	S	W	F	S	T	Y	L	V	T	Q	R
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			B				S	S	B																												S			T	T	T														G	G	G												T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	A	K	T	E	P	N	Y	H	D	L	Y	S	K	V	I	V	A	M	G	S	G	L	L	H	Q	F	M	V	N	V	T	L	R	Q	L	F	V	L	L	S	T	K	D	E	Q	A	I	D	K	K	H	L	K	N	L	A	S	W	L	G	C	I	T	L	A	L	N	K	P	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T	T		G	G	G												T																						B	S		G	G	G	S																T	G	G	G	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	K	H	K	N	I	A	F	R	E	M	L	I	E	A	Y	K	E	N	R	L	E	I	V	V	P	F	V	T	K	I	L	Q	R	A	S	E	S	K	I	F	K	P	P	N	P	W	T	V	G	I	L	K	L	L	I	E	L	N	E	K	A	N	W	K	L	S	L	T	F	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		T	T	T	B													T														T	T	G	G	G		T	T	T	S	T	T																		T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.
Sequence	V	E	V	L	L	K	S	F	N	L	T	T	K	S	L	K	P	S	N	F	I	N	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)								T	T			T	T	S	S				S