PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c4b5sB_

Fold library id	PDB Header	Molecule	Title
c4b5sB_	PDB header: lyase	Chain: B: PDB Molecule: 4-hydroxy-2-oxo-heptane-1,7-dioate aldolase;	PDBTitle: crystal structures of divalent metal dependent pyruvate aldolase,2 hpai, in complex with pyruvate

Links to external resources
Added to library: Sat Sep 1 14:19:40 2012

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence M E N S F K A A L K A G R P Q I G L W L G L S S S Y S A E L L A G A G F D W L L I D G E H A P N N V Q T V L T Q L Q A I A P Y P S Q P V V R

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
S
T S
S S S S S S
T T S S S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence P S W N D P V Q I K Q L L D V G T Q T L L V P M V Q N A D E A R E A V R A T R Y P P A G I R G V G S A L A R A S R W N R I P D Y L Q K A N D

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S S
T T
S
S T S
T T S
G G G
G G G T T T T S T T T G G

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence Q M C V L V Q I E T R E A M K N L P Q I L D V E G V D G V F I G P A D L S A D M G Y A G N P Q H P E V Q A A I E Q A I V Q I R E S G K A P G

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) G
S T S T T
T S T T
S T T

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 .

Sequence I L I A N E Q L A K R Y L E L G A L F V A V G V D T T L L A R A A E A L A A R F G

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
T T

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

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Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	M	E	N	S	F	K	A	A	L	K	A	G	R	P	Q	I	G	L	W	L	G	L	S	S	S	Y	S	A	E	L	L	A	G	A	G	F	D	W	L	L	I	D	G	E	H	A	P	N	N	V	Q	T	V	L	T	Q	L	Q	A	I	A	P	Y	P	S	Q	P	V	V	R
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)											T	T										S											T	S			S						S	S	S	S	S														T	T	S	S	S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	P	S	W	N	D	P	V	Q	I	K	Q	L	L	D	V	G	T	Q	T	L	L	V	P	M	V	Q	N	A	D	E	A	R	E	A	V	R	A	T	R	Y	P	P	A	G	I	R	G	V	G	S	A	L	A	R	A	S	R	W	N	R	I	P	D	Y	L	Q	K	A	N	D
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		S	S	S											T	T							S				S											T	S		T	T	S							G	G	G		G	G	G	T	T	T	T	S	T	T					T	G	G
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	Q	M	C	V	L	V	Q	I	E	T	R	E	A	M	K	N	L	P	Q	I	L	D	V	E	G	V	D	G	V	F	I	G	P	A	D	L	S	A	D	M	G	Y	A	G	N	P	Q	H	P	E	V	Q	A	A	I	E	Q	A	I	V	Q	I	R	E	S	G	K	A	P	G
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	G									S												T	S	T	T																T	S	T	T				S																	T	T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.
Sequence	I	L	I	A	N	E	Q	L	A	K	R	Y	L	E	L	G	A	L	F	V	A	V	G	V	D	T	T	L	L	A	R	A	A	E	A	L	A	A	R	F	G
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)															T	T																							T	T