PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c4aq5B_

Fold library id	PDB Header	Molecule	Title
c4aq5B_	PDB header: membrane protein	Chain: B: PDB Molecule: acetylcholine receptor beta subunit;	PDBTitle: gating movement in acetylcholine receptor analysed by time-2 resolved electron cryo-microscopy (closed class)

Links to external resources
Added to library: Sat Aug 4 13:44:57 2012

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence S V M E D T L L S V L F E N Y N P K V R P S Q T V G D K V T V R V G L T L T S L L I L N E K N E E M T T S V F L N L A W T D Y R L Q W D P A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
S S S
S S
S S S S
T T T T
T T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence A Y E G I K D L S I P S D D V W Q P D I V L M N N N D G S F E I T L H V N V L V Q H T G A V S W H P S A I Y R S S C T I K V M Y F P F D W Q

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S
S
S
S S
S S
S
S S S S S
T T S
S
T T
S S S T T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence N C T M V F K S Y T Y D T S E V I L Q H A L D A M I N Q D A F T E N G Q W S I E H K P S R K N W R S D D P S Y E D V T F Y L I I Q R K P L F

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S
B T S
S G G G
T T
S S B
T T S S S B
B
S

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280

Sequence Y I V Y T I V P C I L I S I L A I L V F Y L P P D A G E K M S L S I S A L L A L T V F L L L L A D K V P E T S L S V P I I I S Y L M F I M I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S T T T T S T T T
G G G G T T T T T T T S S

. . . . . . . . . 290 . . . . . . . . . 300 . . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350

Sequence L V A F S V I L S V V V L N L H H R S P N T H E A V E A I K Y I A E Q L E S A S E F D D L K K D W Q Y V A M V A D R L F L Y I F I T M C S I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
T T T
S
S T T

. . . . . . . . . 360 . . . . . . . . . 370

Sequence G T F S I F L D A S H N V P P D N P F A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S S S T T

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	S	V	M	E	D	T	L	L	S	V	L	F	E	N	Y	N	P	K	V	R	P	S	Q	T	V	G	D	K	V	T	V	R	V	G	L	T	L	T	S	L	L	I	L	N	E	K	N	E	E	M	T	T	S	V	F	L	N	L	A	W	T	D	Y	R	L	Q	W	D	P	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		T	T														S	S	S		S	S		S	S	S	S																		T	T	T	T															T	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	A	Y	E	G	I	K	D	L	S	I	P	S	D	D	V	W	Q	P	D	I	V	L	M	N	N	N	D	G	S	F	E	I	T	L	H	V	N	V	L	V	Q	H	T	G	A	V	S	W	H	P	S	A	I	Y	R	S	S	C	T	I	K	V	M	Y	F	P	F	D	W	Q
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			S	S		S						S		S	S								S	S				S				S	S	S	S	S						T	T	S															S		T	T		S	S	S	T	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	N	C	T	M	V	F	K	S	Y	T	Y	D	T	S	E	V	I	L	Q	H	A	L	D	A	M	I	N	Q	D	A	F	T	E	N	G	Q	W	S	I	E	H	K	P	S	R	K	N	W	R	S	D	D	P	S	Y	E	D	V	T	F	Y	L	I	I	Q	R	K	P	L	F
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)									S	S			B	T	S												S	G	G	G			T	T		S	S	B												T	T	S	S	S	B										B					S
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Sequence	Y	I	V	Y	T	I	V	P	C	I	L	I	S	I	L	A	I	L	V	F	Y	L	P	P	D	A	G	E	K	M	S	L	S	I	S	A	L	L	A	L	T	V	F	L	L	L	L	A	D	K	V	P	E	T	S	L	S	V	P	I	I	I	S	Y	L	M	F	I	M	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S	T	T	T	T																	S	T	T	T		G	G	G	G	T																				T	T	T	T	T	T	S	S
	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
Sequence	L	V	A	F	S	V	I	L	S	V	V	V	L	N	L	H	H	R	S	P	N	T	H	E	A	V	E	A	I	K	Y	I	A	E	Q	L	E	S	A	S	E	F	D	D	L	K	K	D	W	Q	Y	V	A	M	V	A	D	R	L	F	L	Y	I	F	I	T	M	C	S	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																		T		T	T	T																													S		S															T	T
	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370
Sequence	G	T	F	S	I	F	L	D	A	S	H	N	V	P	P	D	N	P	F	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)													S	S	S	S	T	T