PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c4anjA_

Fold library id	PDB Header	Molecule	Title
c4anjA_	PDB header: motor protein/metal-bindng protein	Chain: A: PDB Molecule: unconventional myosin-vi, green fluorescent protein;	PDBTitle: myosin vi (mdinsert2-gfp fusion) pre-powerstroke state (mg.adp.alf4)

Links to external resources
Added to library: Sat Oct 20 16:27:03 2012

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence G K P V W A P H P T D G F Q V G N I V D I G P D S L T I E P L K T F L A L I N Q V F P A E E D S K K D V E D N C S L M Y L N E A T L L H N I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T T
S S
G G G
S
S S
S B G G G S S S
S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence K V R Y S K D R I Y T Y V A N I L I A V N P Y F D I P K I Y S S E T I K S Y Q G K S L G T M P P H V F A I A D K A F R D M K V L K L S Q S I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
T T
S S
T T T T S T T
B T T B
S
T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence I V S G E S G A G K T E N T K F V L R Y L T E S Y G T I D D R I V E A N P L L E A F G N A K T V R N N N S S R F G K F V E I H F N E K S S V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S T T S S
T T T
S S
T T S S
T T S

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280

Sequence V G G F V S H Y L L E K S R I C V Q G K E E R N Y H I F Y R L C A G A S E D I R E R L H L S S P D N F R Y L N R G C T R Y F A N K E T D K Q

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S G G G T
T T
S B
T
G G G
T S
B
T T

. . . . . . . . . 290 . . . . . . . . . 300 . . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350

Sequence I L Q N R K S P E Y L K A G S L K D P L L D D H G D F I R M C T A M K K I G L D D E E K L D L F R V V A G V L H L G N I D F E E C N L K N K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
G G G
B
S S
T
T
G G

. . . . . . . . . 360 . . . . . . . . . 370 . . . . . . . . . 380 . . . . . . . . . 390 . . . . . . . . . 400 . . . . . . . . . 410 . . . . . . . . . 420

Sequence S T Q A L E Y C A E L L G L D Q D D L R V S L T T R V K V P L K V E Q A N N A R D A L A K T V Y S H L F D H V V N R V N Q C F P F E T S S Y

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) G T T
T T S
S
S

. . . . . . . . . 430 . . . . . . . . . 440 . . . . . . . . . 450 . . . . . . . . . 460 . . . . . . . . . 470 . . . . . . . . . 480 . . . . . . . . . 490

Sequence F I G V L D I A G F E Y F E H N S F E Q F C I N Y C N E K L Q Q F F N E R I L K E E Q E L Y Q K E G L G V N E V H Y V D N Q D C I D L I E A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S
T T T T

. . . . . . . . . 500 . . . . . . . . . 510 . . . . . . . . . 520 . . . . . . . . . 530 . . . . . . . . . 540 . . . . . . . . . 550 . . . . . . . . . 560

Sequence R L V G I L D I L D E E N R L P Q P S D Q H F T S A V H Q K H K D H F R L S I P R K S K L A I H R N I R D D E G F I I R H F A G A V C Y E T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T S S S S
T T T T
T T
G G G
S
S T T T T
T T S T T

. . . . . . . . . 570 . . . . . . . . . 580 . . . . . . . . . 590 . . . . . . . . . 600 . . . . . . . . . 610 . . . . . . . . . 620 . . . . . . . . . 630

Sequence T Q F V E K N N D A L H M S L E S L I C E S R D K F I R E L F E S F I S V G N K F K T Q L N L L L D K L R S T G A S F I R C I K P N L K M T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T B
T
S
T T
B T S
S S

. . . . . . . . . 640 . . . . . . . . . 650 . . . . . . . . . 660 . . . . . . . . . 670 . . . . . . . . . 680 . . . . . . . . . 690 . . . . . . . . . 700

Sequence S H H F E G A Q I L S Q L Q C S G M V S V L D L M Q G G F P S R A S F H E L Y N M Y K K Y M P D K L A R L D P R L F C K A L F K A L G L N E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S
T T T T
T T S
S S G G G S
T S
G

. . . . . . . . . 710 . . . . . . . . . 720 . . . . . . . . . 730 . . . . . . . . . 740 . . . . . . . . . 750 . . . . . . . . . 760 . . . . . . . . . 770

Sequence I D Y K F G L T K V F F R P G K F A E F D Q I M K S D P D H L A E L V K R V N H W L I C S R W K K V Q W C S L S V I K L K N K I K Y R A E A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) G G
S S
T T

. . . . . . . . . 780 . . . . . . . . . 790 . . . . . . . . . 800 . . . . . . . . . 810 . . . . . . . . . 820 . . . . . . . . . 830 . . . . . . . . . 840

Sequence V S K G E E L F T G V V P I L V E L D G D V N G H K F S V S G E G E G D A T Y G K L T L K F I C T T G K L P V P W P T L V T T F V Q C F A R

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T S S
T T T T T T T T S S
S S
G G G G T T T
G G G
B

. . . . . . . . . 850 . . . . . . . . . 860 . . . . . . . . . 870 . . . . . . . . . 880 . . . . . . . . . 890 . . . . . . . . . 900 . . . . . . . . . 910

Sequence Y P D H M R Q H D F F K S A M P E G Y V Q E R T I F F K D D G N Y K T R A E V K F E G D T L V N R I E L K G I D F K E D G N I L G H K L E Y

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
G G G G G G
T T T T
T T S
T T S
T T S T T T T T
B
S

. . . . . . . . . 920 . . . . . . . . . 930 . . . . . . . . . 940 . . . . . . . . . 950 . . . . . . . . . 960 . . . . . . . . . 970 . . . . . . . . . 980

Sequence N Y N S H N V Y I M A D K Q K N G I K V N F K I R H N I E D G S V Q L A D H Y Q Q N T P I G D G P V L L P D N H Y L S Y Q S A L S K D P N E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T T T B T T S
S S S S
S
T T

. . . . . . . . . 990 . . . . .

Sequence K R D H M V L L E F V T A A G

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	G	K	P	V	W	A	P	H	P	T	D	G	F	Q	V	G	N	I	V	D	I	G	P	D	S	L	T	I	E	P	L	K	T	F	L	A	L	I	N	Q	V	F	P	A	E	E	D	S	K	K	D	V	E	D	N	C	S	L	M	Y	L	N	E	A	T	L	L	H	N	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)									T	T	T												S	S														G	G	G						S		S	S				S	B	G	G	G	S	S	S		S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	K	V	R	Y	S	K	D	R	I	Y	T	Y	V	A	N	I	L	I	A	V	N	P	Y	F	D	I	P	K	I	Y	S	S	E	T	I	K	S	Y	Q	G	K	S	L	G	T	M	P	P	H	V	F	A	I	A	D	K	A	F	R	D	M	K	V	L	K	L	S	Q	S	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						T	T							T	T								S	S			T	T	T	T	S								T	T			B	T	T	B		S																	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	I	V	S	G	E	S	G	A	G	K	T	E	N	T	K	F	V	L	R	Y	L	T	E	S	Y	G	T	I	D	D	R	I	V	E	A	N	P	L	L	E	A	F	G	N	A	K	T	V	R	N	N	N	S	S	R	F	G	K	F	V	E	I	H	F	N	E	K	S	S	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)					S	T	T	S	S																				T	T					T													S	S		T	T			S	S										T	T	S
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Sequence	V	G	G	F	V	S	H	Y	L	L	E	K	S	R	I	C	V	Q	G	K	E	E	R	N	Y	H	I	F	Y	R	L	C	A	G	A	S	E	D	I	R	E	R	L	H	L	S	S	P	D	N	F	R	Y	L	N	R	G	C	T	R	Y	F	A	N	K	E	T	D	K	Q
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)												S	G	G	G	T				T	T			S	B																			T				G	G	G						T	S					B							T	T
	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
Sequence	I	L	Q	N	R	K	S	P	E	Y	L	K	A	G	S	L	K	D	P	L	L	D	D	H	G	D	F	I	R	M	C	T	A	M	K	K	I	G	L	D	D	E	E	K	L	D	L	F	R	V	V	A	G	V	L	H	L	G	N	I	D	F	E	E	C	N	L	K	N	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S		G	G	G											B			S	S																		T																					T										G	G
	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence	S	T	Q	A	L	E	Y	C	A	E	L	L	G	L	D	Q	D	D	L	R	V	S	L	T	T	R	V	K	V	P	L	K	V	E	Q	A	N	N	A	R	D	A	L	A	K	T	V	Y	S	H	L	F	D	H	V	V	N	R	V	N	Q	C	F	P	F	E	T	S	S	Y
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	G											T	T																																																T	T	S			S			S
	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490
Sequence	F	I	G	V	L	D	I	A	G	F	E	Y	F	E	H	N	S	F	E	Q	F	C	I	N	Y	C	N	E	K	L	Q	Q	F	F	N	E	R	I	L	K	E	E	Q	E	L	Y	Q	K	E	G	L	G	V	N	E	V	H	Y	V	D	N	Q	D	C	I	D	L	I	E	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)														S	S																								T	T									T	T
	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560
Sequence	R	L	V	G	I	L	D	I	L	D	E	E	N	R	L	P	Q	P	S	D	Q	H	F	T	S	A	V	H	Q	K	H	K	D	H	F	R	L	S	I	P	R	K	S	K	L	A	I	H	R	N	I	R	D	D	E	G	F	I	I	R	H	F	A	G	A	V	C	Y	E	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T	T	S											S	S	S													T	T	T	T		T	T				G	G	G		S		S	T	T	T	T			T	T	S							T	T
	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630
Sequence	T	Q	F	V	E	K	N	N	D	A	L	H	M	S	L	E	S	L	I	C	E	S	R	D	K	F	I	R	E	L	F	E	S	F	I	S	V	G	N	K	F	K	T	Q	L	N	L	L	L	D	K	L	R	S	T	G	A	S	F	I	R	C	I	K	P	N	L	K	M	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T						B													T		S							T	T					B																		T	S												S	S
	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700
Sequence	S	H	H	F	E	G	A	Q	I	L	S	Q	L	Q	C	S	G	M	V	S	V	L	D	L	M	Q	G	G	F	P	S	R	A	S	F	H	E	L	Y	N	M	Y	K	K	Y	M	P	D	K	L	A	R	L	D	P	R	L	F	C	K	A	L	F	K	A	L	G	L	N	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S	S															T								T	T	T																	T	T	S		S	S	G	G	G	S													T	S			G
	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770
Sequence	I	D	Y	K	F	G	L	T	K	V	F	F	R	P	G	K	F	A	E	F	D	Q	I	M	K	S	D	P	D	H	L	A	E	L	V	K	R	V	N	H	W	L	I	C	S	R	W	K	K	V	Q	W	C	S	L	S	V	I	K	L	K	N	K	I	K	Y	R	A	E	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	G	G					S	S						T	T
	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840
Sequence	V	S	K	G	E	E	L	F	T	G	V	V	P	I	L	V	E	L	D	G	D	V	N	G	H	K	F	S	V	S	G	E	G	E	G	D	A	T	Y	G	K	L	T	L	K	F	I	C	T	T	G	K	L	P	V	P	W	P	T	L	V	T	T	F	V	Q	C	F	A	R
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)							T	T	S	S													T	T													T	T	T	T									T	T	S	S		S	S		G	G	G	G	T	T	T			G	G	G		B
	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910
Sequence	Y	P	D	H	M	R	Q	H	D	F	F	K	S	A	M	P	E	G	Y	V	Q	E	R	T	I	F	F	K	D	D	G	N	Y	K	T	R	A	E	V	K	F	E	G	D	T	L	V	N	R	I	E	L	K	G	I	D	F	K	E	D	G	N	I	L	G	H	K	L	E	Y
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			G	G	G	G	G	G						T	T	T	T											T	T	S													T	T												S			T	T	S	T	T	T	T	T		B		S
	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980
Sequence	N	Y	N	S	H	N	V	Y	I	M	A	D	K	Q	K	N	G	I	K	V	N	F	K	I	R	H	N	I	E	D	G	S	V	Q	L	A	D	H	Y	Q	Q	N	T	P	I	G	D	G	P	V	L	L	P	D	N	H	Y	L	S	Y	Q	S	A	L	S	K	D	P	N	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)													T	T	T	T												B	T	T	S														S	S	S	S							S													T	T
	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.
Sequence	K	R	D	H	M	V	L	L	E	F	V	T	A	A	G
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		S	S