PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c4aezC_

Fold library id	PDB Header	Molecule	Title
c4aezC_	PDB header: cell cycle	Chain: C: PDB Molecule: mitotic spindle checkpoint component mad3;	PDBTitle: crystal structure of mitotic checkpoint complex

Links to external resources
Added to library: Sat Mar 24 12:07:34 2012

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence N W V H M D V I E Q S K E N I E P R K A G H S A S A L A K S S S R N H T E K E V A G L Q K E R M G H E R K I E T S E S L D D P L Q V W I D Y

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T G G G
T T
T
G G G S S
T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence I K W T L D N F P Q G E T K T S G L V T L L E R C T R E F V R N P L Y K D D V R Y L R I W M Q Y V N Y I D E P V E L F S F L A H H H I G Q E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
T T T
T T T
G G G T T
T T
S
T T
S T T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence S S I F Y E E Y A N Y F E S R G L F Q K A D E V Y Q K G K R M K A K P F L R F Q Q K Y Q Q F T H R W L E F A P Q S F S S N T N S V N P L Q T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) B T T
T
B S
G G G
S
T T

. . . . .

Sequence T F E S T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	N	W	V	H	M	D	V	I	E	Q	S	K	E	N	I	E	P	R	K	A	G	H	S	A	S	A	L	A	K	S	S	S	R	N	H	T	E	K	E	V	A	G	L	Q	K	E	R	M	G	H	E	R	K	I	E	T	S	E	S	L	D	D	P	L	Q	V	W	I	D	Y
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)											T	G	G	G					T	T												T																									G	G	G	S	S		T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	I	K	W	T	L	D	N	F	P	Q	G	E	T	K	T	S	G	L	V	T	L	L	E	R	C	T	R	E	F	V	R	N	P	L	Y	K	D	D	V	R	Y	L	R	I	W	M	Q	Y	V	N	Y	I	D	E	P	V	E	L	F	S	F	L	A	H	H	H	I	G	Q	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)									T	T				T	T	T													T	T	T		G	G	G	T	T													T	T		S												T	T		S	T	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	S	S	I	F	Y	E	E	Y	A	N	Y	F	E	S	R	G	L	F	Q	K	A	D	E	V	Y	Q	K	G	K	R	M	K	A	K	P	F	L	R	F	Q	Q	K	Y	Q	Q	F	T	H	R	W	L	E	F	A	P	Q	S	F	S	S	N	T	N	S	V	N	P	L	Q	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	B														T	T																T		B	S																				G	G	G			S							T	T
	.	.	.	.	.
Sequence	T	F	E	S	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)