PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c4ad7C_

Fold library id	PDB Header	Molecule	Title
c4ad7C_	PDB header: membrane protein	Chain: C: PDB Molecule: glypican-1;	PDBTitle: crystal structure of full-length n-glycosylated human2 glypican-1

Links to external resources
Added to library: Sat Mar 24 12:08:15 2012

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence S R S C G E V R Q I Y G A K G F S L S D V P Q A E I S G E H L R I C P Q G Y T C C T S E M E E N L A N R S H A E L E T A L R D S S R V L Q A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
B
T T
T T S
S B
B
T T
S S S
S S S B S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence M L A T Q L R S F D D H F Q H L L N D S E R T L Q A T F P G A F G E L Y T Q N A R A F R D L Y S E L R L Y Y R G A N L H L E E T L A E F W A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T T T
S
S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence R L L E R L F K Q L H P E A L R P F G E A P R E L R L R A T R A F V A A R S F V Q G L G V A S D V V R K V A Q V P L G P E C S R A V M K L V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S T T T T

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280

Sequence Y C A H C L G V P G A R P C P D Y C R N V L K G C L A N Q A D L D A E W R N L L D S M V L I T D K F W G T S V I G S V H T W L A E A I N A L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T
T T
B
S T T G G G G T T
T T T

. . . . . . . . . 290 . . . . . . . . . 300 . . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350

Sequence Q D N R D T L T A K S G T L E K L V S E A K A Q L R D V Q D F W I S L P G T L C S E K M R C W N G M A R G R Y L P E V M G D G L A N Q I N N

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T S S
T T T
S S S
S
S S S G G G T T

. . . . . . . . . 360 . . . . . . . . . 370 . . . . . . . . . 380 . . . . .

Sequence P E V E V D I T K P D M T I R Q Q I M Q L K I M T N R L R S A Y N G N

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S
S S S
T

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	S	R	S	C	G	E	V	R	Q	I	Y	G	A	K	G	F	S	L	S	D	V	P	Q	A	E	I	S	G	E	H	L	R	I	C	P	Q	G	Y	T	C	C	T	S	E	M	E	E	N	L	A	N	R	S	H	A	E	L	E	T	A	L	R	D	S	S	R	V	L	Q	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			B											T	T			T	T	S			S	B		B			T	T		S	S	S		S	S	S	B	S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	M	L	A	T	Q	L	R	S	F	D	D	H	F	Q	H	L	L	N	D	S	E	R	T	L	Q	A	T	F	P	G	A	F	G	E	L	Y	T	Q	N	A	R	A	F	R	D	L	Y	S	E	L	R	L	Y	Y	R	G	A	N	L	H	L	E	E	T	L	A	E	F	W	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																																	T					T	T																T	T			S		S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	R	L	L	E	R	L	F	K	Q	L	H	P	E	A	L	R	P	F	G	E	A	P	R	E	L	R	L	R	A	T	R	A	F	V	A	A	R	S	F	V	Q	G	L	G	V	A	S	D	V	V	R	K	V	A	Q	V	P	L	G	P	E	C	S	R	A	V	M	K	L	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																	S	S	T	T																																		T	T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Sequence	Y	C	A	H	C	L	G	V	P	G	A	R	P	C	P	D	Y	C	R	N	V	L	K	G	C	L	A	N	Q	A	D	L	D	A	E	W	R	N	L	L	D	S	M	V	L	I	T	D	K	F	W	G	T	S	V	I	G	S	V	H	T	W	L	A	E	A	I	N	A	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T					T	T		T	T			B													S					T	T														G	G	G	G	T	T					T	T	T
	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
Sequence	Q	D	N	R	D	T	L	T	A	K	S	G	T	L	E	K	L	V	S	E	A	K	A	Q	L	R	D	V	Q	D	F	W	I	S	L	P	G	T	L	C	S	E	K	M	R	C	W	N	G	M	A	R	G	R	Y	L	P	E	V	M	G	D	G	L	A	N	Q	I	N	N
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			T	T	S	S																							T	T													T						S	S	S						S					S	S	S	G	G	G	T	T
	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.
Sequence	P	E	V	E	V	D	I	T	K	P	D	M	T	I	R	Q	Q	I	M	Q	L	K	I	M	T	N	R	L	R	S	A	Y	N	G	N
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S	S					S	S	S																									T