PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c3vuoA_

Fold library id	PDB Header	Molecule	Title
c3vuoA_	PDB header: toxin	Chain: A: PDB Molecule: ntnha;	PDBTitle: crystal structure of nontoxic nonhemagglutinin subcomponent (ntnha)2 from clostridium botulinum serotype d strain 4947

Links to external resources
Added to library: Sat Sep 22 14:26:48 2012

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence M D I N D D L N I N S P V D N K N V V I V R A R K T N T F F K A F K V A P N I W V A P E R Y Y G E P L D I A E E Y K L D G G I Y D S N F L S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
T T
S S S S T T S S
T T
S
T T S
S S
G G G
T T
B
T T T T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence Q D S E R E N F L Q A I I T L L K R I N N T I S G K Q L L S L I S T A I P F P Y G Y V G Y R E T N Y I E S Q N N K N F Y A S N I V I F G P G

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S T T S S
B
B B S S B S S S
S
S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence S N I V E N N V I C Y K K N D A E N G M G T M A E I L F Q P L L T Y K Y N K F Y I D P A M E L T K C L I K S L Y F L Y G I K P S D D L V V P

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S B T T
S S G G G G T S S S
S T T
T
T T

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280

Sequence Y R L R T E L D N K Q F S Q L N I I D L L I S G G V D L E F I N T N P Y W F T N S Y F S N S I K M F E K Y K N I Y E T E I E G N N A I G N D

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T S S S
S S G G G G T S
S S
T T T T
T T T

. . . . . . . . . 290 . . . . . . . . . 300 . . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350

Sequence I K L R L K Q K F Q N S V Q D I W N L N L N Y F S K E F N S I I P D R F S N A L K H F Y R K Q Y Y T M D Y G D N Y N I N G F V N G Q I N T K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S
T
S T
S S T T S
T T T S T T T T

. . . . . . . . . 360 . . . . . . . . . 370 . . . . . . . . . 380 . . . . . . . . . 390 . . . . . . . . . 400 . . . . . . . . . 410 . . . . . . . . . 420

Sequence L P L S D K N T N I I S K P E K V V N L V N A N N I S L M K S N I Y G D G L K G T T E D F Y S T Y K I P Y N E E S D N F P L N N I S I E E V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
B
G G G G G
S
T T
S
B
S S
S T T

. . . . . . . . . 430 . . . . . . . . . 440 . . . . . . . . . 450 . . . . . . . . . 460 . . . . . . . . . 470 . . . . . . . . . 480 . . . . . . . . . 490

Sequence D S I P E I I D I N P Y K D N S D D L L F T Q I T S T T E E V I T H T A L P V N Y L Q A Q I I T N E N F T L S S D F S K V V S S K D K S L V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T S
B
T T
S S
T T S
S S
S
T
S S

. . . . . . . . . 500 . . . . . . . . . 510 . . . . . . . . . 520 . . . . . . . . . 530 . . . . . . . . . 540 . . . . . . . . . 550 . . . . . . . . . 560

Sequence Y S F L D N L M S Y L E T I K N D G P I D T D K K Y Y L W L K E V F K N Y S F D I N L T Q E I D S S C G I N E V V I W F G K A L N I L N T S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S T T S
S T
T T T T T S S
S S

. . . . . . . . . 570 . . . . . . . . . 580 . . . . . . . . . 590 . . . . . . . . . 600 . . . . . . . . . 610 . . . . . . . . . 620 . . . . . . . . . 630

Sequence N S F V E E Y Q N S G P I S L I S K K D N L S E P N I E I D D I P D S L L G L S F K D L N N K L Y E I Y S K N R V Y F R K I Y F N F L D Q W

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
G G G G
S
B
S S S T T

. . . . . . . . . 640 . . . . . . . . . 650 . . . . . . . . . 660 . . . . . . . . . 670 . . . . . . . . . 680 . . . . . . . . . 690 . . . . . . . . . 700

Sequence W T E Y Y S Q Y F E L I C M A K Q S I L A Q E S V V K Q I I Q N K F T D L S K A S I P P D T L K L I K E T T E K T F I D L S N E S Q I S M N

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T S
S S S S

. . . . . . . . . 710 . . . . . . . . . 720 . . . . . . . . . 730 . . . . . . . . . 740 . . . . . . . . . 750 . . . . . . . . . 760 . . . . . . . . . 770

Sequence R V D N F L N K A S I C V F V E D I Y P K F I S Y M E K Y I N N I N I K T R E F I Q R C T N I N D N E K S I L I N S Y T F K T I D F K F L N

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
S S
T
G G G S

. . . . . . . . . 780 . . . . . . . . . 790 . . . . . . . . . 800 . . . . . . . . . 810 . . . . . . . . . 820 . . . . . . . . . 830 . . . . . . . . . 840

Sequence I Q A I K N F F N S Q V E Q V M K E M L S P Y Q L L L F A T R G P N S N I I E D I S G K N T L I Q Y T E S V E L V Y G V N G E S L Y L K S P

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T S
T
S T T T T
S S
T T
S S S
S S

. . . . . . . . . 850 . . . . . . . . . 860 . . . . . . . . . 870 . . . . . . . . . 880 . . . . . . . . . 890 . . . . . . . . . 900 . . . . . . . . . 910

Sequence N E T V E F S N N F F T N G L T N N F T I C F W L R F T G K D D D K T R L I G N K V N N C G W E I Y F E D N G L V F E I I D S N G N Q E S V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
G G G G
S S
S S
S S
T T
T T

. . . . . . . . . 920 . . . . . . . . . 930 . . . . . . . . . 940 . . . . . . . . . 950 . . . . . . . . . 960 . . . . . . . . . 970 . . . . . . . . . 980

Sequence Y L S N V I N N N W Y Y I S I S V D R L K D Q L L I F I N D K N V A N V S I E Q I L N I Y S T N V I S L V N K N N S I Y V E E L S V L D K P

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
T T S
T T T T T T
T T
S
S S
S S

. . . . . . . . . 990 . . . . . . . . . 1000 . . . . . . . . . 1010 . . . . . . . . . 1020 . . . . . . . . . 1030 . . . . . . . . . 1040 . . . . . . . . . 1050

Sequence V A S E E V I R N Y F S Y L D N S Y I R D S S K S L L E Y N K N Y Q L Y N Y V F P E T S L Y E V N D N N K S Y L S L K N T D G I N I P S V K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S B
B
T T S
B
B S S
B S S S T T S
S S S
S S T T S S
B

. . . . . . . . . 1060 . . . . . . . . . 1070 . . . . . . . . . 1080 . . . . . . . . . 1090 . . . . . . . . . 1100 . . . . . . . . . 1110 . . . . . . . . . 1120

Sequence F K L I N I D E S K G Y V Q K W D E C I I C V S D G T E K Y L D I S E N N R I Q L V S S K D N A K K I T V N T D L F R P D C I T F S Y N D K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S S S
B
B T T S S S
S S
B S
G G G S
S S
T T T T

. . . . . . . . . 1130 . . . . . . . . . 1140 . . . . . . . . . 1150 .

Sequence Y F S L S L R D G D Y N W M I C N N K V P K G A H L W I L K S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
S S
S S S
G G G

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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Phyre2 is part of Genome3D

	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	M	D	I	N	D	D	L	N	I	N	S	P	V	D	N	K	N	V	V	I	V	R	A	R	K	T	N	T	F	F	K	A	F	K	V	A	P	N	I	W	V	A	P	E	R	Y	Y	G	E	P	L	D	I	A	E	E	Y	K	L	D	G	G	I	Y	D	S	N	F	L	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			S						T	T					S	S	S						S	T	T	S	S										T	T						S			T	T	S		S	S			G	G	G			T	T			B		T	T	T	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	Q	D	S	E	R	E	N	F	L	Q	A	I	I	T	L	L	K	R	I	N	N	T	I	S	G	K	Q	L	L	S	L	I	S	T	A	I	P	F	P	Y	G	Y	V	G	Y	R	E	T	N	Y	I	E	S	Q	N	N	K	N	F	Y	A	S	N	I	V	I	F	G	P	G
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S																		T	T	S	S																		B						B	B	S	S				B	S	S	S							S							S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	S	N	I	V	E	N	N	V	I	C	Y	K	K	N	D	A	E	N	G	M	G	T	M	A	E	I	L	F	Q	P	L	L	T	Y	K	Y	N	K	F	Y	I	D	P	A	M	E	L	T	K	C	L	I	K	S	L	Y	F	L	Y	G	I	K	P	S	D	D	L	V	V	P
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S	B	T	T							S	S	G	G	G	G	T	S	S	S											S						T	T																						T					T	T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Sequence	Y	R	L	R	T	E	L	D	N	K	Q	F	S	Q	L	N	I	I	D	L	L	I	S	G	G	V	D	L	E	F	I	N	T	N	P	Y	W	F	T	N	S	Y	F	S	N	S	I	K	M	F	E	K	Y	K	N	I	Y	E	T	E	I	E	G	N	N	A	I	G	N	D
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)					T	T	S	S	S																S	S	G	G	G	G	T	S		S	S																									T	T	T	T		T	T	T
	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
Sequence	I	K	L	R	L	K	Q	K	F	Q	N	S	V	Q	D	I	W	N	L	N	L	N	Y	F	S	K	E	F	N	S	I	I	P	D	R	F	S	N	A	L	K	H	F	Y	R	K	Q	Y	Y	T	M	D	Y	G	D	N	Y	N	I	N	G	F	V	N	G	Q	I	N	T	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)										S	S							T		S									T						S	S	T	T	S														T	T	T	S			T	T			T	T
	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence	L	P	L	S	D	K	N	T	N	I	I	S	K	P	E	K	V	V	N	L	V	N	A	N	N	I	S	L	M	K	S	N	I	Y	G	D	G	L	K	G	T	T	E	D	F	Y	S	T	Y	K	I	P	Y	N	E	E	S	D	N	F	P	L	N	N	I	S	I	E	E	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			B		G	G	G	G	G						S								T	T																			S							B			S	S								S	T	T
	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490
Sequence	D	S	I	P	E	I	I	D	I	N	P	Y	K	D	N	S	D	D	L	L	F	T	Q	I	T	S	T	T	E	E	V	I	T	H	T	A	L	P	V	N	Y	L	Q	A	Q	I	I	T	N	E	N	F	T	L	S	S	D	F	S	K	V	V	S	S	K	D	K	S	L	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T	S								B		T	T																				S	S									T	T	S				S	S					S							T		S	S
	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560
Sequence	Y	S	F	L	D	N	L	M	S	Y	L	E	T	I	K	N	D	G	P	I	D	T	D	K	K	Y	Y	L	W	L	K	E	V	F	K	N	Y	S	F	D	I	N	L	T	Q	E	I	D	S	S	C	G	I	N	E	V	V	I	W	F	G	K	A	L	N	I	L	N	T	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)														S	T	T	S					S																				T								T	T							T	T						T	S	S		S	S
	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630
Sequence	N	S	F	V	E	E	Y	Q	N	S	G	P	I	S	L	I	S	K	K	D	N	L	S	E	P	N	I	E	I	D	D	I	P	D	S	L	L	G	L	S	F	K	D	L	N	N	K	L	Y	E	I	Y	S	K	N	R	V	Y	F	R	K	I	Y	F	N	F	L	D	Q	W
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S											G	G	G	G		S									B								S	S	S	T	T
	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700
Sequence	W	T	E	Y	Y	S	Q	Y	F	E	L	I	C	M	A	K	Q	S	I	L	A	Q	E	S	V	V	K	Q	I	I	Q	N	K	F	T	D	L	S	K	A	S	I	P	P	D	T	L	K	L	I	K	E	T	T	E	K	T	F	I	D	L	S	N	E	S	Q	I	S	M	N
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				T																															T	T	S		S	S	S	S
	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770
Sequence	R	V	D	N	F	L	N	K	A	S	I	C	V	F	V	E	D	I	Y	P	K	F	I	S	Y	M	E	K	Y	I	N	N	I	N	I	K	T	R	E	F	I	Q	R	C	T	N	I	N	D	N	E	K	S	I	L	I	N	S	Y	T	F	K	T	I	D	F	K	F	L	N
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																	T	T																											S	S													T				G	G	G	S
	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840
Sequence	I	Q	A	I	K	N	F	F	N	S	Q	V	E	Q	V	M	K	E	M	L	S	P	Y	Q	L	L	L	F	A	T	R	G	P	N	S	N	I	I	E	D	I	S	G	K	N	T	L	I	Q	Y	T	E	S	V	E	L	V	Y	G	V	N	G	E	S	L	Y	L	K	S	P
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)							T	T	S											T		S											T	T							T	T		S	S							T	T							S	S	S							S	S
	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910
Sequence	N	E	T	V	E	F	S	N	N	F	F	T	N	G	L	T	N	N	F	T	I	C	F	W	L	R	F	T	G	K	D	D	D	K	T	R	L	I	G	N	K	V	N	N	C	G	W	E	I	Y	F	E	D	N	G	L	V	F	E	I	I	D	S	N	G	N	Q	E	S	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S								G	G	G	G			S	S																S	S										S	S									T	T									T	T
	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980
Sequence	Y	L	S	N	V	I	N	N	N	W	Y	Y	I	S	I	S	V	D	R	L	K	D	Q	L	L	I	F	I	N	D	K	N	V	A	N	V	S	I	E	Q	I	L	N	I	Y	S	T	N	V	I	S	L	V	N	K	N	N	S	I	Y	V	E	E	L	S	V	L	D	K	P
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				S		T	T	S											T	T	T	T							T	T									T	T								S								S	S											S	S
	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.	.	.	.	.	.	.	.	.	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.	.	.	.	.	.	.	1050
Sequence	V	A	S	E	E	V	I	R	N	Y	F	S	Y	L	D	N	S	Y	I	R	D	S	S	K	S	L	L	E	Y	N	K	N	Y	Q	L	Y	N	Y	V	F	P	E	T	S	L	Y	E	V	N	D	N	N	K	S	Y	L	S	L	K	N	T	D	G	I	N	I	P	S	V	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																S	S	B		B		T	T	S		B		B	S	S			B					S	S	S	T	T	S								S	S	S							S	S	T	T	S	S			B
	.	.	.	.	.	.	.	.	.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.	.	.	.	.	.	.	1080	.	.	.	.	.	.	.	.	.	1090	.	.	.	.	.	.	.	.	.	1100	.	.	.	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120
Sequence	F	K	L	I	N	I	D	E	S	K	G	Y	V	Q	K	W	D	E	C	I	I	C	V	S	D	G	T	E	K	Y	L	D	I	S	E	N	N	R	I	Q	L	V	S	S	K	D	N	A	K	K	I	T	V	N	T	D	L	F	R	P	D	C	I	T	F	S	Y	N	D	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						S	S	S	S			B		B	T	T									S	S	S								S	S		B					S		G	G	G	S									S	S		T	T							T	T
	.	.	.	.	.	.	.	.	.	1130	.	.	.	.	.	.	.	.	.	1140	.	.	.	.	.	.	.	.	.	1150	.
Sequence	Y	F	S	L	S	L	R	D	G	D	Y	N	W	M	I	C	N	N	K	V	P	K	G	A	H	L	W	I	L	K	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)							S		S	S								S	S	S		G	G	G