PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c3vl3A_

Fold library id	PDB Header	Molecule	Title
c3vl3A_	PDB header: oxidoreductase	Chain: A: PDB Molecule: 3-isopropylmalate dehydrogenase;	PDBTitle: 3-isopropylmalate dehydrogenase from shewanella oneidensis mr-1 at 3402 mpa

Links to external resources
Added to library: Sat Mar 3 11:42:32 2012

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence S S Y Q I A V L A G D G I G P E V M A E A R K V L K A V E A R F G L N I E Y T E Y D V G G I A I D N H G C P L P E A T L K G C E A A D A I L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S T T T
T S S S S
T S S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence F G S V G G P K W E K L P P N E Q P E R G A L L P L R G H F E L F C N L R P A K L H D G L E H M S P L R S D I S A R G F D V L C V R E L T G

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
G G G T T S
T T T S T T
T T
G G G S S S
S S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence G I Y F G K P K G R Q G E G E S E E A F D T M R Y S R R E I S R I A R I A F E A A R G R R K K V T S V D K A N V L A C S V L W R Q V V E E V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T T
S S
G G G
T T T S
T T T

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280

Sequence A V D F P D V E L E H I Y I D N A T M Q L L R R P D E F D V M L C S N L F G D I L S D E I A M L T G S M G L L S S A S M N S T G F G L F E P

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) G G G
T T S
G G G
S
S
G G G
T T S

. . . . . . . . . 290 . . . . . . . . . 300 . . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350

Sequence A G G S A P D I A G K G I A N P I A Q I L S A A L M L R H S L K Q E E A A S A I E R A V T K A L N S G Y L T G E L L S S D Q R H K A K T T V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S
G G G T T T T
S
T S
T T
G G G S
G G G G G G

. . . . . . . . . 360 . . . .

Sequence Q M G D F I A D A V K A G V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	S	S	Y	Q	I	A	V	L	A	G	D	G	I	G	P	E	V	M	A	E	A	R	K	V	L	K	A	V	E	A	R	F	G	L	N	I	E	Y	T	E	Y	D	V	G	G	I	A	I	D	N	H	G	C	P	L	P	E	A	T	L	K	G	C	E	A	A	D	A	I	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)											S	T	T																				T											T								S	S	S	S										T	S	S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	F	G	S	V	G	G	P	K	W	E	K	L	P	P	N	E	Q	P	E	R	G	A	L	L	P	L	R	G	H	F	E	L	F	C	N	L	R	P	A	K	L	H	D	G	L	E	H	M	S	P	L	R	S	D	I	S	A	R	G	F	D	V	L	C	V	R	E	L	T	G
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)							G	G	G	T	T	S		T	T	T	S													T	T												T	T		G	G	G	S	S	S																		S	S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	G	I	Y	F	G	K	P	K	G	R	Q	G	E	G	E	S	E	E	A	F	D	T	M	R	Y	S	R	R	E	I	S	R	I	A	R	I	A	F	E	A	A	R	G	R	R	K	K	V	T	S	V	D	K	A	N	V	L	A	C	S	V	L	W	R	Q	V	V	E	E	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T	T	T		S	S							G	G	G																											T	T	T	S								T	T	T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Sequence	A	V	D	F	P	D	V	E	L	E	H	I	Y	I	D	N	A	T	M	Q	L	L	R	R	P	D	E	F	D	V	M	L	C	S	N	L	F	G	D	I	L	S	D	E	I	A	M	L	T	G	S	M	G	L	L	S	S	A	S	M	N	S	T	G	F	G	L	F	E	P
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	G	G	G		T	T	S																		G	G	G		S																					S		G	G	G								T	T	S
	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
Sequence	A	G	G	S	A	P	D	I	A	G	K	G	I	A	N	P	I	A	Q	I	L	S	A	A	L	M	L	R	H	S	L	K	Q	E	E	A	A	S	A	I	E	R	A	V	T	K	A	L	N	S	G	Y	L	T	G	E	L	L	S	S	D	Q	R	H	K	A	K	T	T	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S	S				G	G	G	T	T	T	T		S																T	S																			T	T				G	G	G	S		G	G	G	G	G	G
	.	.	.	.	.	.	.	.	.	360	.	.	.	.
Sequence	Q	M	G	D	F	I	A	D	A	V	K	A	G	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)												T	T