PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c3uwoA_

Fold library id	PDB Header	Molecule	Title
c3uwoA_	PDB header: transferase/transferase inhibitor	Chain: A: PDB Molecule: thymidylate kinase;	PDBTitle: structure guided development of novel thymidine mimetics targeting2 pseudomonas aeruginosa thymidylate kinase: from hit to lead3 generation

Links to external resources
Added to library: Sat Feb 4 17:49:12 2012

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence G L F V T L E G P E G A G K S T N R D Y L A E R L R E R G I E V Q L T R E P G G T P L A E R I R E L L L A P S D E P M A A D T E L L L M F A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T S S T T T
S S
S S S
S S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence A R A Q H L A G V I R P A L A R G A V V L C D R F T D A T Y A Y Q G G G R G L P E A R I A A L E S F V Q G D L R P D L T L V F D L P V R L D

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T
S
T T T T T
T T
S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . .

Sequence R F E Q E D R R F F E A V R Q T Y L Q R A A Q A P E R Y Q V L D A G L P L A E V Q A G L D R L L P N L L E R

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T T
S G G G T T S

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

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Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	G	L	F	V	T	L	E	G	P	E	G	A	G	K	S	T	N	R	D	Y	L	A	E	R	L	R	E	R	G	I	E	V	Q	L	T	R	E	P	G	G	T	P	L	A	E	R	I	R	E	L	L	L	A	P	S	D	E	P	M	A	A	D	T	E	L	L	L	M	F	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)										T	T	S	S														T	T	T								S	S		S	S												S			S	S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	A	R	A	Q	H	L	A	G	V	I	R	P	A	L	A	R	G	A	V	V	L	C	D	R	F	T	D	A	T	Y	A	Y	Q	G	G	G	R	G	L	P	E	A	R	I	A	A	L	E	S	F	V	Q	G	D	L	R	P	D	L	T	L	V	F	D	L	P	V	R	L	D
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)									T							T	T							S									T	T	T	T	T																T	T				S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.
Sequence	R	F	E	Q	E	D	R	R	F	F	E	A	V	R	Q	T	Y	L	Q	R	A	A	Q	A	P	E	R	Y	Q	V	L	D	A	G	L	P	L	A	E	V	Q	A	G	L	D	R	L	L	P	N	L	L	E	R
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T	T	T																				S	G	G	G						T	T	S