PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c3tm4A_

Fold library id	PDB Header	Molecule	Title
c3tm4A_	PDB header: transferase	Chain: A: PDB Molecule: trna (guanine n2-)-methyltransferase trm14;	PDBTitle: crystal structure of trm14 from pyrococcus furiosus in complex with s-2 adenosylmethionine

Links to external resources
Added to library: Sat Mar 17 12:02:35 2012

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence M K F L L T T A Q G I E D I A K R E V S L L L K K L G I S F Q I E E K P L G I E G R L L L E A E K A Y Y V D E K G R K R E L S I S T Y L N E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
T T T
S G G G
T T
T T S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence N S R L L H R V I I E I A S E K F N G I E K D E S E E A L K R I K D F V S S L P V E Q F V K V S E T F A V R S F R K G D H N I T S I D I A R

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S
S
T T T T T S
T S
G G G G S
T T S S S
S S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence T V G E A I F E R L S R F G T P L V N L D H P A V I F R A E L I K D V F F L G I D T T G D S S L H K R P W R V Y D H P A H L K A S I A N A M

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T S
S S S
S T T S S
S S
T T
T T
S
T T

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280

Sequence I E L A E L D G G S V L D P M C G S G T I L I E L A L R R Y S G E I I G I E K Y R K H L I G A E M N A L A A G V L D K I K F I Q G D A T Q L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
S
T T
T T
T T
S
S
T T
G G G
G G G G

. . . . . . . . . 290 . . . . . . . . . 300 . . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350

Sequence S Q Y V D S V D F A I S N L P Y G S M I P D L Y M K F F N E L A K V L E K R G V F I T T E K K A I E E A I A E N G F E I I H H R V I G H G G

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) G G T
S
S
T T T T

. . . . . . . . . 360 . . . .

Sequence L M V H L Y V V K L E H H H

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	M	K	F	L	L	T	T	A	Q	G	I	E	D	I	A	K	R	E	V	S	L	L	L	K	K	L	G	I	S	F	Q	I	E	E	K	P	L	G	I	E	G	R	L	L	L	E	A	E	K	A	Y	Y	V	D	E	K	G	R	K	R	E	L	S	I	S	T	Y	L	N	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)									T	T															T	T	T								S	G	G	G		T	T														T	T	S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	N	S	R	L	L	H	R	V	I	I	E	I	A	S	E	K	F	N	G	I	E	K	D	E	S	E	E	A	L	K	R	I	K	D	F	V	S	S	L	P	V	E	Q	F	V	K	V	S	E	T	F	A	V	R	S	F	R	K	G	D	H	N	I	T	S	I	D	I	A	R
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			S	S		S												T	T	T	T	T	S															T	S		G	G	G	G	S		T	T	S										S	S		S	S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	T	V	G	E	A	I	F	E	R	L	S	R	F	G	T	P	L	V	N	L	D	H	P	A	V	I	F	R	A	E	L	I	K	D	V	F	F	L	G	I	D	T	T	G	D	S	S	L	H	K	R	P	W	R	V	Y	D	H	P	A	H	L	K	A	S	I	A	N	A	M
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)												T	T	S						S	S	S		S									T	T								S	S		S	S		T	T			T	T			S			T	T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Sequence	I	E	L	A	E	L	D	G	G	S	V	L	D	P	M	C	G	S	G	T	I	L	I	E	L	A	L	R	R	Y	S	G	E	I	I	G	I	E	K	Y	R	K	H	L	I	G	A	E	M	N	A	L	A	A	G	V	L	D	K	I	K	F	I	Q	G	D	A	T	Q	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)					T			S						T	T		T	T										T	T			S							S															T	T		G	G	G								G	G	G	G
	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
Sequence	S	Q	Y	V	D	S	V	D	F	A	I	S	N	L	P	Y	G	S	M	I	P	D	L	Y	M	K	F	F	N	E	L	A	K	V	L	E	K	R	G	V	F	I	T	T	E	K	K	A	I	E	E	A	I	A	E	N	G	F	E	I	I	H	H	R	V	I	G	H	G	G
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	G	G	T		S																																							S												T	T												T	T
	.	.	.	.	.	.	.	.	.	360	.	.	.	.
Sequence	L	M	V	H	L	Y	V	V	K	L	E	H	H	H
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)											T	T