PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c3tdnB_

Fold library id	PDB Header	Molecule	Title
c3tdnB_	PDB header: de novo protein	Chain: B: PDB Molecule: flr symmetric alpha-beta tim barrel;	PDBTitle: computationally designed two-fold symmetric tim-barrel protein, flr

Links to external resources
Added to library: Thu Jan 10 03:52:05 2013

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence S Q A V V V A I D A K R V D G E F M V F T Y S G K K N T G I L L R D W V V E V E K R G A G E I L L T S I D R D G T K S G Y D T E M I R F V R

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T T T T T T T T
S T T T T T
S S
G

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence P L T T L P I I A S G G A G K M E H F L E A F L R G A D K V S I N T A A V E N P S L I T Q I A Q T F G S Q A V V V A I D A K R V D G E F M V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) G G
S S
S S
S T T
S S
T
G G G T T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence F T Y S G K K N T G I L L R D W V V E V E K R G A G E I L L T S I S G Y D T E M I R F V R P L T T L P I I A S G G A G K M E H F L E A F L R

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T T T
S
G G G
S
S S
S T

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . .

Sequence G A D K V S I N T A A V E N P S L I T Q I A Q T F G

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
S S
T

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	S	Q	A	V	V	V	A	I	D	A	K	R	V	D	G	E	F	M	V	F	T	Y	S	G	K	K	N	T	G	I	L	L	R	D	W	V	V	E	V	E	K	R	G	A	G	E	I	L	L	T	S	I	D	R	D	G	T	K	S	G	Y	D	T	E	M	I	R	F	V	R
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		T	T											T	T							T	T	T	T																		T		S							T	T	T	T	T		S	S											G
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	P	L	T	T	L	P	I	I	A	S	G	G	A	G	K	M	E	H	F	L	E	A	F	L	R	G	A	D	K	V	S	I	N	T	A	A	V	E	N	P	S	L	I	T	Q	I	A	Q	T	F	G	S	Q	A	V	V	V	A	I	D	A	K	R	V	D	G	E	F	M	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	G	G		S	S						S	S			S										T	T		S					S							T												G	G	G											T	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	F	T	Y	S	G	K	K	N	T	G	I	L	L	R	D	W	V	V	E	V	E	K	R	G	A	G	E	I	L	L	T	S	I	S	G	Y	D	T	E	M	I	R	F	V	R	P	L	T	T	L	P	I	I	A	S	G	G	A	G	K	M	E	H	F	L	E	A	F	L	R
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			T	T	T	T																		T		S																			G	G	G			S						S	S			S										T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.
Sequence	G	A	D	K	V	S	I	N	T	A	A	V	E	N	P	S	L	I	T	Q	I	A	Q	T	F	G
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T		S					S							T