PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c3sc0A_

Fold library id	PDB Header	Molecule	Title
c3sc0A_	PDB header: oxidoreductase	Chain: A: PDB Molecule: methylmalonic aciduria and homocystinuria type c protein;	PDBTitle: crystal structure of mmachc (1-238), a human b12 processing enzyme,2 complexed with methylcobalamin

Links to external resources
Added to library: Sun Jun 26 11:21:08 2011

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence E P K V A E L K Q K I E D T L C P F G F E V Y P F Q V A W Y N E L L P P A F H L P L P G P T L A F L V L S T P A M F D R A L K P F L Q S C H

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
G G G T T T S
G G G
S S
T T
T T T T T S T T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence L R M L T D P V D Q C V A Y H L G R V R E S L P E L Q I E I I A D Y E V H P N R R P K I L A Q T A A H V A G A A Y Y Y Q R Q D V E A D P W G

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S S
T T S
T T
B
T T S
B S S
T T S S
G G G S T T
S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence N Q R I S G V C I H P R F G G W F A I R G V V L L P G I E V P D L P P R K P H D C V P T R A D R I A L L E G F N F H W R D W T Y R D A V T P

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S
B T T T B T S
T T
S
S
G G G
G G G G S S

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . .

Sequence Q E R Y S E E Q K A Y F S T P P A Q R L A L L G L A Q

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S
T T
T T S
S T T T

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

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Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	E	P	K	V	A	E	L	K	Q	K	I	E	D	T	L	C	P	F	G	F	E	V	Y	P	F	Q	V	A	W	Y	N	E	L	L	P	P	A	F	H	L	P	L	P	G	P	T	L	A	F	L	V	L	S	T	P	A	M	F	D	R	A	L	K	P	F	L	Q	S	C	H
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																G	G	G	T													T	T	S		G	G	G			S	S		T	T										T	T					T					T	T	S	T	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	L	R	M	L	T	D	P	V	D	Q	C	V	A	Y	H	L	G	R	V	R	E	S	L	P	E	L	Q	I	E	I	I	A	D	Y	E	V	H	P	N	R	R	P	K	I	L	A	Q	T	A	A	H	V	A	G	A	A	Y	Y	Y	Q	R	Q	D	V	E	A	D	P	W	G
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			S	S	S																			T	T	S							T	T		B		T	T	S		B	S	S									T	T	S	S					G	G	G	S	T	T		S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	N	Q	R	I	S	G	V	C	I	H	P	R	F	G	G	W	F	A	I	R	G	V	V	L	L	P	G	I	E	V	P	D	L	P	P	R	K	P	H	D	C	V	P	T	R	A	D	R	I	A	L	L	E	G	F	N	F	H	W	R	D	W	T	Y	R	D	A	V	T	P
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S	S								B	T	T	T	B	T	S															T	T										S		S															G	G	G		G	G	G	G	S	S
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.
Sequence	Q	E	R	Y	S	E	E	Q	K	A	Y	F	S	T	P	P	A	Q	R	L	A	L	L	G	L	A	Q
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S	S										T	T						T	T	S		S	T	T	T