PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c3rq4A_

Fold library id	PDB Header	Molecule	Title
c3rq4A_	PDB header: transferase	Chain: A: PDB Molecule: histone-lysine n-methyltransferase suv420h2;	PDBTitle: crystal structure of suppressor of variegation 4-20 homolog 2

Links to external resources
Added to library: Sat Jun 4 09:12:45 2011

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence D R V T A R E L C E N D D L A T S L V L D P Y L G F R T H K M N V S P V P P L R R Q Q H L R S A L E T F L R Q R D L E A A Y R A L T L G G W

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T S
S S
T T T T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence T A R Y F Q S R G P R Q E A A L K T H V Y R Y L R A F L P E S G F T I L P C T R Y S M E T N G A K I V S T R A W K K N E K L E L L V G C I A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T T T S
T S G G G
T T
S S
S S
B
T T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence E L R E A D E G L L R A G E N D F S I M Y S T R K R S A Q L W L G P A A F I N H D C K P N C K F V P A D G N A A C V K V L R D I E P G D E V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
G G G G G G
T T T S
T T T T T T S G G G G
S S
S T T T S S
B
T T
B

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240

Sequence T C F Y G E G F F G E K N E H C E C H T C E R K G E G A F R

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T S S S G G G T T
T
G G G

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	D	R	V	T	A	R	E	L	C	E	N	D	D	L	A	T	S	L	V	L	D	P	Y	L	G	F	R	T	H	K	M	N	V	S	P	V	P	P	L	R	R	Q	Q	H	L	R	S	A	L	E	T	F	L	R	Q	R	D	L	E	A	A	Y	R	A	L	T	L	G	G	W
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																									T	S							S	S																																	T	T	T	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	T	A	R	Y	F	Q	S	R	G	P	R	Q	E	A	A	L	K	T	H	V	Y	R	Y	L	R	A	F	L	P	E	S	G	F	T	I	L	P	C	T	R	Y	S	M	E	T	N	G	A	K	I	V	S	T	R	A	W	K	K	N	E	K	L	E	L	L	V	G	C	I	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T	T	T	T	S																					T	S	G	G	G											T	T		S	S							S	S		B		T	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	E	L	R	E	A	D	E	G	L	L	R	A	G	E	N	D	F	S	I	M	Y	S	T	R	K	R	S	A	Q	L	W	L	G	P	A	A	F	I	N	H	D	C	K	P	N	C	K	F	V	P	A	D	G	N	A	A	C	V	K	V	L	R	D	I	E	P	G	D	E	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				G	G	G	G	G	G			T	T	T	S		T	T					T	T	T	T							S	G	G	G	G					S	S		S							T	T	T							S	S		B		T	T		B
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence	T	C	F	Y	G	E	G	F	F	G	E	K	N	E	H	C	E	C	H	T	C	E	R	K	G	E	G	A	F	R
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						T	T	S	S	S	G	G	G	T	T										T		G	G	G