PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c3ooiA_

Fold library id	PDB Header	Molecule	Title
c3ooiA_	PDB header: transferase	Chain: A: PDB Molecule: histone-lysine n-methyltransferase, h3 lysine-36 and h4	PDBTitle: crystal structure of human histone-lysine n-methyltransferase nsd1 set2 domain in complex with s-adenosyl-l-methionine

Links to external resources
Added to library: Tue Dec 28 19:59:58 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence S K E L R Q L Q E D R K N D K K P P P Y K H I K V N R P I G R V Q I F T A D L S E I P R C N C K A T D E N P C G I D S E C I N R M L L Y E C

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
S S
T T
G G G S
S
T T S S S T T
T T S
T T B

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence H P T V C P A G G R C Q N Q C F S K R Q Y P E V E I F R T L Q R G W G L R T K T D I K K G E F V N E Y V G E L I D E E E C R A R I R Y A Q E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T T
T T G G G
T
S S S S S S
B
T T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence H D I T N F Y M L T L D K D R I I D A G P K G N Y A R F M N H C C Q P N C E T Q K W S V N G D T R V G L F A L S D I K A G T E L T F N Y N L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
T T
G G G G
S S
S T T S S
B
T T
B
T T

. . . . . . . . . 220 . . . . . . . . . 230 . .

Sequence E C L G N G K T V C K C G A P N C S G F L G

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S T T
T T
B
T T
S B

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

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Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	S	K	E	L	R	Q	L	Q	E	D	R	K	N	D	K	K	P	P	P	Y	K	H	I	K	V	N	R	P	I	G	R	V	Q	I	F	T	A	D	L	S	E	I	P	R	C	N	C	K	A	T	D	E	N	P	C	G	I	D	S	E	C	I	N	R	M	L	L	Y	E	C
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																S								S	S					T	T								G	G	G	S				S			T	T	S	S	S	T	T		T	T	S							T	T	B
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	H	P	T	V	C	P	A	G	G	R	C	Q	N	Q	C	F	S	K	R	Q	Y	P	E	V	E	I	F	R	T	L	Q	R	G	W	G	L	R	T	K	T	D	I	K	K	G	E	F	V	N	E	Y	V	G	E	L	I	D	E	E	E	C	R	A	R	I	R	Y	A	Q	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		T	T	T		T	T	G	G	G									T											S	S	S	S						S	S		B		T	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	H	D	I	T	N	F	Y	M	L	T	L	D	K	D	R	I	I	D	A	G	P	K	G	N	Y	A	R	F	M	N	H	C	C	Q	P	N	C	E	T	Q	K	W	S	V	N	G	D	T	R	V	G	L	F	A	L	S	D	I	K	A	G	T	E	L	T	F	N	Y	N	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T											T	T											G	G	G	G					S	S		S									T	T									S	S		B		T	T		B						T	T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.
Sequence	E	C	L	G	N	G	K	T	V	C	K	C	G	A	P	N	C	S	G	F	L	G
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		S	T	T		T	T		B						T	T			S	B