PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c3mcnA_

Fold library id	PDB Header	Molecule	Title
c3mcnA_	PDB header: transferase	Chain: A: PDB Molecule: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine	PDBTitle: crystal structure of the 6-hyroxymethyl-7,8-dihydropterin2 pyrophosphokinase dihydropteroate synthase bifunctional enzyme from3 francisella tularensis

Links to external resources
Added to library: Tue Dec 28 19:59:55 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence M V Q Y I I G I G T N S G F T I E N I H L A I T A L E S Q Q N I R I I R K A S L Y S S K A D I R F L N T A V K I S S S L K P D E L L V L L K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S S T S T T
S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence D I E L K I G R P R V I D L D I L A A E D L I L E T D K L T I P H K E L I N R S F A L A P L L E L S K G W H H P K Y V E W D L N I R L K E L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
S
T T
S S
S
T T G G G
T T
T T
T T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence G E I V K L K Q T L A N T I R M G I V N L S N Q S F S D G N F D D N Q R K L N L D E L I Q S G A E I I D I G A E S A K P I S I E E E F N K L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
S S
S T T S
B T T B
T T T
S

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280

Sequence N E F L E Y F K S Q L A N L I Y K P L V S I D T R K L E V M Q K I L A K H H D I I W M I N D V E C N N I E Q K A Q L I A K Y N K K Y V I I H

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T G G G
S S
G G G
S S
S S T

. . . . . . . . . 290 . . . . . . . . . 300 . . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350

Sequence N Y I E Q K K Q I L L K H G I A Q Q N I Y F D I G F G L K A L V G H S R K P S V L G L K D S N L A T L D R A T R E L S R K L E K L D I D I I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T
G G G
T T
T T
S

. . . . .

Sequence R V H K I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	M	V	Q	Y	I	I	G	I	G	T	N	S	G	F	T	I	E	N	I	H	L	A	I	T	A	L	E	S	Q	Q	N	I	R	I	I	R	K	A	S	L	Y	S	S	K	A	D	I	R	F	L	N	T	A	V	K	I	S	S	S	L	K	P	D	E	L	L	V	L	L	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)												S	S	S														T	S	T	T																												S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	D	I	E	L	K	I	G	R	P	R	V	I	D	L	D	I	L	A	A	E	D	L	I	L	E	T	D	K	L	T	I	P	H	K	E	L	I	N	R	S	F	A	L	A	P	L	L	E	L	S	K	G	W	H	H	P	K	Y	V	E	W	D	L	N	I	R	L	K	E	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						T	T				S									T	T						S	S				S		T	T	G	G	G													T	T				T	T		T	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	G	E	I	V	K	L	K	Q	T	L	A	N	T	I	R	M	G	I	V	N	L	S	N	Q	S	F	S	D	G	N	F	D	D	N	Q	R	K	L	N	L	D	E	L	I	Q	S	G	A	E	I	I	D	I	G	A	E	S	A	K	P	I	S	I	E	E	E	F	N	K	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)							S					S	S									S	T	T	S				B	T	T	B		T												T	T		S
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Sequence	N	E	F	L	E	Y	F	K	S	Q	L	A	N	L	I	Y	K	P	L	V	S	I	D	T	R	K	L	E	V	M	Q	K	I	L	A	K	H	H	D	I	I	W	M	I	N	D	V	E	C	N	N	I	E	Q	K	A	Q	L	I	A	K	Y	N	K	K	Y	V	I	I	H
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)										T	G	G	G		S	S																						G	G	G							S	S		S	S												T
	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
Sequence	N	Y	I	E	Q	K	K	Q	I	L	L	K	H	G	I	A	Q	Q	N	I	Y	F	D	I	G	F	G	L	K	A	L	V	G	H	S	R	K	P	S	V	L	G	L	K	D	S	N	L	A	T	L	D	R	A	T	R	E	L	S	R	K	L	E	K	L	D	I	D	I	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)														T			G	G	G																T	T																													T	T		S
	.	.	.	.	.
Sequence	R	V	H	K	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			S