PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c3m1iC_

Fold library id	PDB Header	Molecule	Title
c3m1iC_	PDB header: protein transport	Chain: C: PDB Molecule: exportin-1;	PDBTitle: crystal structure of yeast crm1 (xpo1p) in complex with yeast ranbp12 (yrb1p) and yeast rangtp (gsp1pgtp)

Links to external resources
Added to library: Sun Aug 29 06:03:05 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence G A M E G I L D F S N D L D I A L L D Q V V S T F Y Q G S G V Q Q K Q A Q E I L T K F Q D N P D A W Q K A D Q I L Q F S T N P Q S K F I A L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
G G G G G G
T T S
S T T G G G G
S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence S I L D K L I T R K W K L L P N D H R I G I R N F V V G M I I S M C Q D D E V F K T Q K N L I N K S D L T L V Q I L K Q E W P Q N W P E F I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T G G G S
T T T T
T T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence P E L I G S S S S S V N V C E N N M I V L K L L S E E V F D F S A E Q M T Q A K A L H L K N S M S K E F E Q I F K L C F Q V L E Q G S S S S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
T S
T T T S

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280

Sequence L I V A T L E S L L R Y L H W I P Y R Y I Y E T N I L E L L S T K F M T S P D T R A I T L K C L T E V S N L K I P Q D N D L I K R Q T V L F

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T S
T S S S T S
T T

. . . . . . . . . 290 . . . . . . . . . 300 . . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350

Sequence F Q N T L Q Q I A T S V M P V T A D L K A T Y A N A N G N D Q S F L Q D L A M F L T T Y L A R N R A L L E S D E S L R E L L L N A H Q Y L I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
T T S
T
T T S
G G G

. . . . . . . . . 360 . . . . . . . . . 370 . . . . . . . . . 380 . . . . . . . . . 390 . . . . . . . . . 400 . . . . . . . . . 410 . . . . . . . . . 420

Sequence Q L S K I E E R E L F K T T L D Y W H N L V A D L F Y E P L K K H I Y E E I C S Q L R L V I I E N M V R P E E V L V V E N D E G E I V R E F

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T S S
S T T
G G G G T
T T
T T S
S

. . . . . . . . . 430 . . . . . . . . . 440 . . . . . . . . . 450 . . . . . . . . . 460 . . . . . . . . . 470 . . . . . . . . . 480 . . . . . . . . . 490

Sequence V K E S D T I Q L Y K S E R E V L V Y L T H L N V I D T E E I M I S K L A R Q I D G S E W S W H N I N T L S W A I G S I S G T M S E D T E K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
T S S S
T T T S S

. . . . . . . . . 500 . . . . . . . . . 510 . . . . . . . . . 520 . . . . . . . . . 530 . . . . . . . . . 540 . . . . . . . . . 550 . . . . . . . . . 560

Sequence R F V V T V I K D L L D L T V K K R G K D N K A V V A S D I M Y V V G Q Y P R F L K A H W N F L R T V I L K L F E F M H E T H E G V Q D M A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T S S
S
T T S S

. . . . . . . . . 570 . . . . . . . . . 580 . . . . . . . . . 590 . . . . . . . . . 600 . . . . . . . . . 610 . . . . . . . . . 620 . . . . . . . . . 630

Sequence C D T F I K I V Q K C K Y H F V I Q Q P R E S E P F I Q T I I R D I Q K T T A D L Q P Q Q V H T F Y K A C G I I I S E E R S V A E R N R L L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T S
T T
S S
T T T S
T
S

. . . . . . . . . 640 . . . . . . . . . 650 . . . . . . . . . 660 . . . . . . . . . 670 . . . . . . . . . 680 . . . . . . . . . 690 . . . . . . . . . 700

Sequence S D L M Q L P N M A W D T I V E Q S T A N P T L L L D S E T V K I I A N I I K T N V A V C T S M G A D F Y P Q L G H I Y Y N M L Q L Y R A V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
G G G G G S G G G G

. . . . . . . . . 710 . . . . . . . . . 720 . . . . . . . . . 730 . . . . . . . . . 740 . . . . . . . . . 750 . . . . . . . . . 760 . . . . . . . . . 770

Sequence S S M I S A Q V A A E G L I A T K T P K V R G L R T I K K E I L K L V E T Y I S K A R N L D D V V K V L V E P L L N A V L E D Y M N N V P D

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
G G G G G S
S
T S
G G

. . . . . . . . . 780 . . . . . . . . . 790 . . . . . . . . . 800 . . . . . . . . . 810 . . . . . . . . . 820 . . . . . . . . . 830 . . . . . . . . . 840

Sequence A R D A E V L N C M T T V V E K V G H M I P Q G V I L I L Q S V F E C T L D M I N K D F T E Y P E H R V E F Y K L L K V I N E K S F A A F L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) G
T G G G
S S
S S S S
T

. . . . . . . . . 850 . . . . . . . . . 860 . . . . . . . . . 870 . . . . . . . . . 880 . . . . . . . . . 890 . . . . . . . . . 900 . . . . . . . . . 910

Sequence E L P P A A F K L F V D A I C W A F K H N N R D V E V N G L Q I A L D L V K N I E R M G N V P F A N E F H K N Y F F I F V S E T F F V L T D

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
T
S S
S
S

. . . . . . . . . 920 . . . . . . . . . 930 . . . . . . . . . 940 . . . . . . . . . 950 . . . . . . . . . 960 . . . . . . . . . 970 . . . . . . . . . 980

Sequence S D H K S G F S K Q A L L L M K L I S L V Y D N K I S V P L Y Q E A E V P Q G T S N Q V Y L S Q Y L A N M L S N A F P H L T S E Q I A S F L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
G G G T T
S
S S
G G G S S T T
T T S

. . . . . . . . . 990 . . . . . . . . . 1000 . . . . . . . . . 1010 . . . . . . . . . 1020 . . .

Sequence S A L T K Q Y K D L V V F K G T L R D F L V Q I K E V G G D P T D Y L F A E D K E N A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
T S S S
G G G G G G G G G T T T

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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Phyre2 is part of Genome3D

	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	G	A	M	E	G	I	L	D	F	S	N	D	L	D	I	A	L	L	D	Q	V	V	S	T	F	Y	Q	G	S	G	V	Q	Q	K	Q	A	Q	E	I	L	T	K	F	Q	D	N	P	D	A	W	Q	K	A	D	Q	I	L	Q	F	S	T	N	P	Q	S	K	F	I	A	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		G	G	G	G	G	G		T	T	S																																			S	T	T	G	G	G	G									S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	S	I	L	D	K	L	I	T	R	K	W	K	L	L	P	N	D	H	R	I	G	I	R	N	F	V	V	G	M	I	I	S	M	C	Q	D	D	E	V	F	K	T	Q	K	N	L	I	N	K	S	D	L	T	L	V	Q	I	L	K	Q	E	W	P	Q	N	W	P	E	F	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)										T	G	G	G	S																																																T	T	T	T		T	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	P	E	L	I	G	S	S	S	S	S	V	N	V	C	E	N	N	M	I	V	L	K	L	L	S	E	E	V	F	D	F	S	A	E	Q	M	T	Q	A	K	A	L	H	L	K	N	S	M	S	K	E	F	E	Q	I	F	K	L	C	F	Q	V	L	E	Q	G	S	S	S	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)								T	T																					T	S		T	T	T	S
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Sequence	L	I	V	A	T	L	E	S	L	L	R	Y	L	H	W	I	P	Y	R	Y	I	Y	E	T	N	I	L	E	L	L	S	T	K	F	M	T	S	P	D	T	R	A	I	T	L	K	C	L	T	E	V	S	N	L	K	I	P	Q	D	N	D	L	I	K	R	Q	T	V	L	F
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)													T	T	T	S		T					S	S	S							T					S																					T	T
	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
Sequence	F	Q	N	T	L	Q	Q	I	A	T	S	V	M	P	V	T	A	D	L	K	A	T	Y	A	N	A	N	G	N	D	Q	S	F	L	Q	D	L	A	M	F	L	T	T	Y	L	A	R	N	R	A	L	L	E	S	D	E	S	L	R	E	L	L	L	N	A	H	Q	Y	L	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)												T			T	T	S									T		T	T																									S		G	G	G
	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence	Q	L	S	K	I	E	E	R	E	L	F	K	T	T	L	D	Y	W	H	N	L	V	A	D	L	F	Y	E	P	L	K	K	H	I	Y	E	E	I	C	S	Q	L	R	L	V	I	I	E	N	M	V	R	P	E	E	V	L	V	V	E	N	D	E	G	E	I	V	R	E	F
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				T	S	S																						S	T	T		G	G	G	G														T					T	T							T	T	S						S
	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490
Sequence	V	K	E	S	D	T	I	Q	L	Y	K	S	E	R	E	V	L	V	Y	L	T	H	L	N	V	I	D	T	E	E	I	M	I	S	K	L	A	R	Q	I	D	G	S	E	W	S	W	H	N	I	N	T	L	S	W	A	I	G	S	I	S	G	T	M	S	E	D	T	E	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S																																								T	S	S	S																T	T	T	S	S
	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560
Sequence	R	F	V	V	T	V	I	K	D	L	L	D	L	T	V	K	K	R	G	K	D	N	K	A	V	V	A	S	D	I	M	Y	V	V	G	Q	Y	P	R	F	L	K	A	H	W	N	F	L	R	T	V	I	L	K	L	F	E	F	M	H	E	T	H	E	G	V	Q	D	M	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)														T	T	S	S		S																																								T	T	S	S
	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630
Sequence	C	D	T	F	I	K	I	V	Q	K	C	K	Y	H	F	V	I	Q	Q	P	R	E	S	E	P	F	I	Q	T	I	I	R	D	I	Q	K	T	T	A	D	L	Q	P	Q	Q	V	H	T	F	Y	K	A	C	G	I	I	I	S	E	E	R	S	V	A	E	R	N	R	L	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)												T					S			T	T		S	S									T						T	T	S																		T			S
	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700
Sequence	S	D	L	M	Q	L	P	N	M	A	W	D	T	I	V	E	Q	S	T	A	N	P	T	L	L	L	D	S	E	T	V	K	I	I	A	N	I	I	K	T	N	V	A	V	C	T	S	M	G	A	D	F	Y	P	Q	L	G	H	I	Y	Y	N	M	L	Q	L	Y	R	A	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				T																		G	G	G	G	G	S																						G	G	G	G
	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770
Sequence	S	S	M	I	S	A	Q	V	A	A	E	G	L	I	A	T	K	T	P	K	V	R	G	L	R	T	I	K	K	E	I	L	K	L	V	E	T	Y	I	S	K	A	R	N	L	D	D	V	V	K	V	L	V	E	P	L	L	N	A	V	L	E	D	Y	M	N	N	V	P	D
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)													G	G	G	G	G	S																									S									T															S		G	G
	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840
Sequence	A	R	D	A	E	V	L	N	C	M	T	T	V	V	E	K	V	G	H	M	I	P	Q	G	V	I	L	I	L	Q	S	V	F	E	C	T	L	D	M	I	N	K	D	F	T	E	Y	P	E	H	R	V	E	F	Y	K	L	L	K	V	I	N	E	K	S	F	A	A	F	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	G			T														G	G	G																					S	S		S	S	S	S																			T
	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910
Sequence	E	L	P	P	A	A	F	K	L	F	V	D	A	I	C	W	A	F	K	H	N	N	R	D	V	E	V	N	G	L	Q	I	A	L	D	L	V	K	N	I	E	R	M	G	N	V	P	F	A	N	E	F	H	K	N	Y	F	F	I	F	V	S	E	T	F	F	V	L	T	D
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		S																	T			S																					S		S																									S
	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980
Sequence	S	D	H	K	S	G	F	S	K	Q	A	L	L	L	M	K	L	I	S	L	V	Y	D	N	K	I	S	V	P	L	Y	Q	E	A	E	V	P	Q	G	T	S	N	Q	V	Y	L	S	Q	Y	L	A	N	M	L	S	N	A	F	P	H	L	T	S	E	Q	I	A	S	F	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T		G	G	G																	T	T				S		S	S		G	G	G	S	S	T	T																				T	T	S
	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.	.	.
Sequence	S	A	L	T	K	Q	Y	K	D	L	V	V	F	K	G	T	L	R	D	F	L	V	Q	I	K	E	V	G	G	D	P	T	D	Y	L	F	A	E	D	K	E	N	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)							T	T																	T	S	S	S			G	G	G	G	G	G	G	G	G	T	T	T