PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c3lkwA_

Fold library id	PDB Header	Molecule	Title
c3lkwA_	PDB header: viral protein,hydrolase	Chain: A: PDB Molecule: fusion protein of nonstructural protein 2b and	PDBTitle: crystal structure of dengue virus 1 ns2b/ns3 protease active2 site mutant

Links to external resources
Added to library: Sun Aug 29 02:52:48 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence H M A D L S L E K A A E V S W E E E A E H S G A S H N I L V E V Q D D G T M K I K V L W D T P S P G I Y R I L Q R G L L G R S Q V G V G V F

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
T T
S S
T T S
S S
T T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence Q E G V F H T M W H V T R G A V L M Y Q G K R L E P S W A S V K K D L I S Y G G G W R F Q G S W N A G E E V Q V I A V E P G K N P K N V Q T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
T T
T T
T T T T S S S
T T
T T S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence A P G T F K T P E G E V G A I A L D F K P G T A G S P I V N R E G K I V G L Y G N G V V T T S G T Y V S A I A Q A K A S Q E G P L P E I E D

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
T T
T T
T T S
S
T T S
B

.

Sequence E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	H	M	A	D	L	S	L	E	K	A	A	E	V	S	W	E	E	E	A	E	H	S	G	A	S	H	N	I	L	V	E	V	Q	D	D	G	T	M	K	I	K	V	L	W	D	T	P	S	P	G	I	Y	R	I	L	Q	R	G	L	L	G	R	S	Q	V	G	V	G	V	F
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			S														T	T					S	S										T	T	S									S	S													T	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	Q	E	G	V	F	H	T	M	W	H	V	T	R	G	A	V	L	M	Y	Q	G	K	R	L	E	P	S	W	A	S	V	K	K	D	L	I	S	Y	G	G	G	W	R	F	Q	G	S	W	N	A	G	E	E	V	Q	V	I	A	V	E	P	G	K	N	P	K	N	V	Q	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		T	T										T	T						T	T										T	T	T	T					S	S	S									T	T										T	T	S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	A	P	G	T	F	K	T	P	E	G	E	V	G	A	I	A	L	D	F	K	P	G	T	A	G	S	P	I	V	N	R	E	G	K	I	V	G	L	Y	G	N	G	V	V	T	T	S	G	T	Y	V	S	A	I	A	Q	A	K	A	S	Q	E	G	P	L	P	E	I	E	D
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)								T	T												T	T		T	T						T	T	S						S							T	T	S							B
	.
Sequence	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)