PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c3kwvF_

Fold library id	PDB Header	Molecule	Title
c3kwvF_	PDB header: toxin/protein transport	Chain: F: PDB Molecule: lethal factor;	PDBTitle: structural basis for the unfolding of anthrax lethal factor by2 protective antigen oligomers

Links to external resources
Added to library: Sat Nov 20 08:50:51 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence N K T Q E E H L K E I M K H I V K I E V K G E E A V K K E A A E K L L E K V P S D V L E M Y K A I G G K I Y I V D G D I T K H I S L E A L S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
T
S
S S S
S S S
S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence E D K K K I K D I Y G K D A L L H E H Y V Y A K E G Y E P V L V I Q S S E D Y V E N T E K A L N V Y Y E I G K I L S R D I L S K I N Q P Y Q

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) G G G G
T T S
G G G
S
S S S
G G G G T
T T T T T T T
T T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence K F L D V L N T I K N A S D S D G Q D L L F T N Q L K E H P T D F S V E F L E Q N S N E V Q E V F A K A F A Y Y I E P Q H R D V L Q L Y A P

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S S
S S S
T T T T T
S
T T T S

. . . . . . . . . 220 . .

Sequence E A F N Y M D K F N E Q

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	N	K	T	Q	E	E	H	L	K	E	I	M	K	H	I	V	K	I	E	V	K	G	E	E	A	V	K	K	E	A	A	E	K	L	L	E	K	V	P	S	D	V	L	E	M	Y	K	A	I	G	G	K	I	Y	I	V	D	G	D	I	T	K	H	I	S	L	E	A	L	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																																						S											T									S		S	S	S		S	S	S		S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	E	D	K	K	K	I	K	D	I	Y	G	K	D	A	L	L	H	E	H	Y	V	Y	A	K	E	G	Y	E	P	V	L	V	I	Q	S	S	E	D	Y	V	E	N	T	E	K	A	L	N	V	Y	Y	E	I	G	K	I	L	S	R	D	I	L	S	K	I	N	Q	P	Y	Q
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	G	G	G	G					T	T	S					G	G	G		S						S	S	S									G	G	G	G	T																		T	T	T	T	T	T	T		T	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	K	F	L	D	V	L	N	T	I	K	N	A	S	D	S	D	G	Q	D	L	L	F	T	N	Q	L	K	E	H	P	T	D	F	S	V	E	F	L	E	Q	N	S	N	E	V	Q	E	V	F	A	K	A	F	A	Y	Y	I	E	P	Q	H	R	D	V	L	Q	L	Y	A	P
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)											S	S	S		S						S	S		T	T	T	T	T			S				T	T					T																	S
	.	.	.	.	.	.	.	.	.	220	.	.
Sequence	E	A	F	N	Y	M	D	K	F	N	E	Q
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)