PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.0

Fold library entry viewer: c3k54A_

Fold library id	PDB Header	Molecule	Title
c3k54A_	PDB header: transferase	Chain: A: PDB Molecule: tyrosine-protein kinase btk;	PDBTitle: structures of human bruton's tyrosine kinase in active and2 inactive conformations suggests a mechanism of activation3 for tec family kinases.

Links to external resources
Added to library: Sat Aug 28 21:14:22 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence Y G S W E I D P K D L T F L K E L G T G Q F G V V K Y G K W R G Q Y D V A I K M I K E F I E E A K V M M N L S H E K L V Q L Y G V C T K Q R

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
G G G B
G G G S T T S S
T T T
T T
T T B
S S S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence P I F I I T E Y M A N G C L L N Y L R E M R H R F Q T Q Q L L E M C K D V C E A M E Y L E S K Q F L H R D L A A R N C L V N D Q G V V K V S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
T T
G G G
T T
S
S G G G
T T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence D F G F P V R W S P P E V L M Y S K F S S K S D I W A F G V L M W E I Y S L G K M P Y E R F T N S E T A E H I A Q G L R L Y R P H L A S E K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
G G G
T T S
T T T T S
T T
T T S

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . .

Sequence V Y T I M Y S C W H E K A D E R P T F K I L L S N I L D V M D E E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
S S G G G S

Download: PDB structure FASTA sequence
Hidden Markov model

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Kelley LA et al. Nature Protocols 10, 845-858 (2015) [paper] [Citation link]

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Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	Y	G	S	W	E	I	D	P	K	D	L	T	F	L	K	E	L	G	T	G	Q	F	G	V	V	K	Y	G	K	W	R	G	Q	Y	D	V	A	I	K	M	I	K	E	F	I	E	E	A	K	V	M	M	N	L	S	H	E	K	L	V	Q	L	Y	G	V	C	T	K	Q	R
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		G	G	G	B			G	G	G									S	T	T	S	S								T	T	T												T	T											T	T	B									S	S	S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	P	I	F	I	I	T	E	Y	M	A	N	G	C	L	L	N	Y	L	R	E	M	R	H	R	F	Q	T	Q	Q	L	L	E	M	C	K	D	V	C	E	A	M	E	Y	L	E	S	K	Q	F	L	H	R	D	L	A	A	R	N	C	L	V	N	D	Q	G	V	V	K	V	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S									T	T										G	G	G																								T	T				S			S	G	G	G					T	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	D	F	G	F	P	V	R	W	S	P	P	E	V	L	M	Y	S	K	F	S	S	K	S	D	I	W	A	F	G	V	L	M	W	E	I	Y	S	L	G	K	M	P	Y	E	R	F	T	N	S	E	T	A	E	H	I	A	Q	G	L	R	L	Y	R	P	H	L	A	S	E	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						G	G	G																													T	T	S			T	T	T	T	S											T	T							T	T	S
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.
Sequence	V	Y	T	I	M	Y	S	C	W	H	E	K	A	D	E	R	P	T	F	K	I	L	L	S	N	I	L	D	V	M	D	E	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)								T	T		S	S	G	G	G	S