PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c3hs8A_

Fold library id	PDB Header	Molecule	Title
c3hs8A_	PDB header: endocytosis	Chain: A: PDB Molecule: adaptor protein complex ap-2, alpha 2 subunit;	PDBTitle: intersectin 1-peptide-ap2 alpha ear complex

Links to external resources
Added to library: Sat Aug 28 17:27:34 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence F E D N F A R F V C K N N G V L F E N Q L L Q I G L K S E F R Q N L G R M F I F Y G N K T S T Q F L N F T P T L I C A D D L Q T N L N L Q T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
G G G G S S
S
S S T T
S S S
B B S
T T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence K P V D P T V D G G A Q V Q Q V V N I E C I S D F T E A P V L N I Q F R Y G G T F Q N V S V K L P I T L N K F F Q P T E M A S Q D F F Q R W

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
B
T T
S
T T
G G G G

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence K Q L S N P Q Q E V Q N I F K A K H P M D T E I T K A K I I G F G S A L L E E V D P N P A N F V G A G I I H T K T T Q I G C L L R L E P N L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S G G G
S S
T
T T S S S S T T S
S S
T

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . .

Sequence Q A Q M Y R L T L R T S K D T V S Q R L C E L L S E Q F

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T S S T T

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	F	E	D	N	F	A	R	F	V	C	K	N	N	G	V	L	F	E	N	Q	L	L	Q	I	G	L	K	S	E	F	R	Q	N	L	G	R	M	F	I	F	Y	G	N	K	T	S	T	Q	F	L	N	F	T	P	T	L	I	C	A	D	D	L	Q	T	N	L	N	L	Q	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)					G	G	G	G	S	S		S								S	S											T	T												S	S	S		B	B	S									T	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	K	P	V	D	P	T	V	D	G	G	A	Q	V	Q	Q	V	V	N	I	E	C	I	S	D	F	T	E	A	P	V	L	N	I	Q	F	R	Y	G	G	T	F	Q	N	V	S	V	K	L	P	I	T	L	N	K	F	F	Q	P	T	E	M	A	S	Q	D	F	F	Q	R	W
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)					S		B		T	T													S															T	T													G	G	G	G
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	K	Q	L	S	N	P	Q	Q	E	V	Q	N	I	F	K	A	K	H	P	M	D	T	E	I	T	K	A	K	I	I	G	F	G	S	A	L	L	E	E	V	D	P	N	P	A	N	F	V	G	A	G	I	I	H	T	K	T	T	Q	I	G	C	L	L	R	L	E	P	N	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)					S	G	G	G									S	S															T					T	T	S	S	S	S	T	T	S										S	S													T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.
Sequence	Q	A	Q	M	Y	R	L	T	L	R	T	S	K	D	T	V	S	Q	R	L	C	E	L	L	S	E	Q	F
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T	T									S	S													T	T