PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.0

Fold library entry viewer: c3egyX_

Fold library id	PDB Header	Molecule	Title
c3egyX_	PDB header: transferase	Chain: X: PDB Molecule: thymidylate synthase;	PDBTitle: crystal structure of human thymidyalte synthase a191k with loop 181-2 197 stabilized in the inactive conformation

Links to external resources
Added to library: Thu Jan 10 05:38:42 2013

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence P P H G E L Q Y L G Q I Q H I L R G V R K D D R T G T G T L S V F G M Q A R Y S L R D E F P L L T T K R V F W K G V L E E L L W F I K G S T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T
T T
S S S
T T T T
T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence V Y G F Q W R H F G G V D Q L Q R V I D T I K T N P D D R R I I M A W N P R D L P L M K L P P H A L Q F Y V V N S E L S C Q L Y Q R S G D M

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
B
B
T T
S
G G G T T T S S S
B
T T T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence G L G V P F N I A S Y A L L T Y M I A H I T G L K P G D F I H T L G D A H I Y L N H I E P L K I Q L Q R E P R P F P K L R I L R K V E K I D

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T
G G G T T S
S
S G G

. . . . . . . . . 220 . . . . . . . . . 230

Sequence D F K A E D F Q I E G Y N P H P T I K M

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) G
G G G S

Download: PDB structure FASTA sequence
Hidden Markov model

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Please cite: The Phyre2 web portal for protein modeling, prediction and analysis

Kelley LA et al. Nature Protocols 10, 845-858 (2015) [paper] [Citation link]

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	P	P	H	G	E	L	Q	Y	L	G	Q	I	Q	H	I	L	R	G	V	R	K	D	D	R	T	G	T	G	T	L	S	V	F	G	M	Q	A	R	Y	S	L	R	D	E	F	P	L	L	T	T	K	R	V	F	W	K	G	V	L	E	E	L	L	W	F	I	K	G	S	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				T																				T	T																	S	S	S					T	T	T	T																T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	V	Y	G	F	Q	W	R	H	F	G	G	V	D	Q	L	Q	R	V	I	D	T	I	K	T	N	P	D	D	R	R	I	I	M	A	W	N	P	R	D	L	P	L	M	K	L	P	P	H	A	L	Q	F	Y	V	V	N	S	E	L	S	C	Q	L	Y	Q	R	S	G	D	M
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)									B			B														T	T		S								G	G	G	T	T	T	S	S	S				B							T	T													T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	G	L	G	V	P	F	N	I	A	S	Y	A	L	L	T	Y	M	I	A	H	I	T	G	L	K	P	G	D	F	I	H	T	L	G	D	A	H	I	Y	L	N	H	I	E	P	L	K	I	Q	L	Q	R	E	P	R	P	F	P	K	L	R	I	L	R	K	V	E	K	I	D
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T																					T																	G	G	G								T	T	S												S				S	G	G
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230
Sequence	D	F	K	A	E	D	F	Q	I	E	G	Y	N	P	H	P	T	I	K	M
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	G			G	G	G					S