PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c3dshA_

Fold library id	PDB Header	Molecule	Title
c3dshA_	PDB header: dna binding protein	Chain: A: PDB Molecule: interferon regulatory factor 5;	PDBTitle: crystal structure of dimeric interferon regulatory factor 52 (irf-5) transactivation domain

Links to external resources
Added to library: Tue Mar 16 13:33:48 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence E Q L L P D L L I S P H M L P L T D L E I K F Q Y R G R P P R A L T I S N P H G C R L F Y S Q L E A T Q E Q V E L F G P I S L E Q V R F P S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T S S T T T S
T T
T T S
T T
S S
G G G
T T S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence P E D I P S D K Q R F Y T N Q L L D V L D R G L I L Q L Q G Q D L Y A I R L C Q C K V F W S G P C A S A H D S C P N P I Q R E V K T K L F S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
T T
S S
T T
S S S
S T T S
S
S S
B
B T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence L E H F L N E L I L F Q K G Q T N T P P P F E I F F C F G E E W P D R K P R E K K L I T V Q V V P V A A R L L L E M F S G E L S W S A D D I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T S
S S
S S
S S
S S
G G G
S T
S S

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . .

Sequence R L Q I S N P D L K D R M V E Q F K E L H H I W Q S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	E	Q	L	L	P	D	L	L	I	S	P	H	M	L	P	L	T	D	L	E	I	K	F	Q	Y	R	G	R	P	P	R	A	L	T	I	S	N	P	H	G	C	R	L	F	Y	S	Q	L	E	A	T	Q	E	Q	V	E	L	F	G	P	I	S	L	E	Q	V	R	F	P	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		T	T						S	S	T	T	T	S		T	T									T	T	S										T	T								S	S				G	G	G							T	T	S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	P	E	D	I	P	S	D	K	Q	R	F	Y	T	N	Q	L	L	D	V	L	D	R	G	L	I	L	Q	L	Q	G	Q	D	L	Y	A	I	R	L	C	Q	C	K	V	F	W	S	G	P	C	A	S	A	H	D	S	C	P	N	P	I	Q	R	E	V	K	T	K	L	F	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		T	T															T	T		S	S								T	T								S	S	S						S	T	T	S			S		S	S			B			B	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	L	E	H	F	L	N	E	L	I	L	F	Q	K	G	Q	T	N	T	P	P	P	F	E	I	F	F	C	F	G	E	E	W	P	D	R	K	P	R	E	K	K	L	I	T	V	Q	V	V	P	V	A	A	R	L	L	L	E	M	F	S	G	E	L	S	W	S	A	D	D	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)													T	T	S		S	S											S	S		S	S		S	S		G	G	G		S																			T				S	S
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.
Sequence	R	L	Q	I	S	N	P	D	L	K	D	R	M	V	E	Q	F	K	E	L	H	H	I	W	Q	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)