PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c3csiA_

Fold library id	PDB Header	Molecule	Title
c3csiA_	PDB header: transferase	Chain: A: PDB Molecule: glutathione s-transferase p;	PDBTitle: crystal structure of the glutathione transferase pi allelic2 variant*c, i104v/a113v, in complex with the chlorambucil-3 glutathione conjugate

Links to external resources
Added to library: Tue Mar 16 13:37:28 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence P P Y T V V Y F P V R G R C A A L R M L L A D Q G Q S W K E E V V T V E T W Q E G S L K A S C L Y G Q L P K F Q D G D L T L Y Q S N T I L R

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S S G G G T T
S S T T S
S
T T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence H L G R T L G L Y G K D Q Q E A A L V D M V N D G V E D L R C K Y V S L I Y T N Y E V G K D D Y V K A L P G Q L K P F E T L L S Q N Q G G K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
S
S S T T S G G G T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . .

Sequence T F I V G D Q I S F A D Y N L L D L L L I H E V L A P G C L D A F P L L S A Y V G R L S A R P K L K A F L A S P E Y V N L P I N G N G K Q

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
S S T T S
S T T G G G G
T S S T S
S S S S S

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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All images and data generated by Phyre2 are free to use in any publication with acknowledgement
Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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Phyre2 is part of Genome3D

	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	P	P	Y	T	V	V	Y	F	P	V	R	G	R	C	A	A	L	R	M	L	L	A	D	Q	G	Q	S	W	K	E	E	V	V	T	V	E	T	W	Q	E	G	S	L	K	A	S	C	L	Y	G	Q	L	P	K	F	Q	D	G	D	L	T	L	Y	Q	S	N	T	I	L	R
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)									S	S	S	G	G	G										T	T																S						S	T	T	S		S						T	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	H	L	G	R	T	L	G	L	Y	G	K	D	Q	Q	E	A	A	L	V	D	M	V	N	D	G	V	E	D	L	R	C	K	Y	V	S	L	I	Y	T	N	Y	E	V	G	K	D	D	Y	V	K	A	L	P	G	Q	L	K	P	F	E	T	L	L	S	Q	N	Q	G	G	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)							T		S		S	S																												T																									T	S	G	G	G	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.
Sequence	T	F	I	V	G	D	Q	I	S	F	A	D	Y	N	L	L	D	L	L	L	I	H	E	V	L	A	P	G	C	L	D	A	F	P	L	L	S	A	Y	V	G	R	L	S	A	R	P	K	L	K	A	F	L	A	S	P	E	Y	V	N	L	P	I	N	G	N	G	K	Q
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S		S	S	T	T	S																			S	T	T	G	G	G	G													T	S									S					T	S		S	S	S	S	S