PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c3cl5A_

Fold library id	PDB Header	Molecule	Title
c3cl5A_	PDB header: hydrolase	Chain: A: PDB Molecule: hemagglutinin-esterase;	PDBTitle: structure of coronavirus hemagglutinin-esterase in complex2 with 4,9-o-diacetyl sialic acid

Links to external resources
Added to library: Tue Mar 16 13:52:34 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence F D N P P T N V V S H L N G D W F L F G D A R S D C N H V V N T N P R N Y S Y M D L N P A L C D S G K I S S K A G N S I F R S F H F T D F Y

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
B S
B S S S
G G G
G G G G G G S S S
T T
S S
G G G T T S S
T T
B S S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence N Y T G E G Q Q I I F Y E G V N F T P Y H A F K C T T S G S N D I W M Q N K G L F Y T Q V Y K N M A V Y R S L T F V N V P Y V Y N G S A Q S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
T T S S G G G
S S T T
T T
S S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence T A L C K S G S L V L N N P A Y I A R E A N F G D Y Y Y K V E A D F Y L S G C D E Y I V P L C I F N G K F L S N T K Y Y D D S Q Y Y F N K D

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S T T B
S S
T T
S S S
S
T T
T T

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280

Sequence T G V I Y G L N S T E T I T T G F D F N C H Y L V L P S G N Y L A I S N E L L L T V P T K A I C L N K R K D F T P V Q V V D S R W N N A R Q

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
S S S
S S
S
T T S

. . . . . . . . . 290 . . . . . . . . . 300 . . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350

Sequence S D N M T A V A C Q P P Y C Y F R N S T T N Y V G V Y D I N H G D A G F T S I L S G L L Y D S P C F S Q Q G V F R Y D N V S S V W P L Y S Y

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T T
S S
T T G G G G S B
S T T S
S S B
S S
S S

. . . . . . . .

Sequence G R C P T A A D

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
B

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

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Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	F	D	N	P	P	T	N	V	V	S	H	L	N	G	D	W	F	L	F	G	D	A	R	S	D	C	N	H	V	V	N	T	N	P	R	N	Y	S	Y	M	D	L	N	P	A	L	C	D	S	G	K	I	S	S	K	A	G	N	S	I	F	R	S	F	H	F	T	D	F	Y
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						B	S				B	S	S	S								G	G	G		G	G	G	G	G	G	S	S	S				T	T		S	S		G	G	G	T	T	S	S						T	T									B	S	S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	N	Y	T	G	E	G	Q	Q	I	I	F	Y	E	G	V	N	F	T	P	Y	H	A	F	K	C	T	T	S	G	S	N	D	I	W	M	Q	N	K	G	L	F	Y	T	Q	V	Y	K	N	M	A	V	Y	R	S	L	T	F	V	N	V	P	Y	V	Y	N	G	S	A	Q	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)							S								T	T	S	S	G	G	G				S	S	T	T																						T	T															S	S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	T	A	L	C	K	S	G	S	L	V	L	N	N	P	A	Y	I	A	R	E	A	N	F	G	D	Y	Y	Y	K	V	E	A	D	F	Y	L	S	G	C	D	E	Y	I	V	P	L	C	I	F	N	G	K	F	L	S	N	T	K	Y	Y	D	D	S	Q	Y	Y	F	N	K	D
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				S			T	T			B		S	S							T	T		S	S	S																									S					T	T												T	T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Sequence	T	G	V	I	Y	G	L	N	S	T	E	T	I	T	T	G	F	D	F	N	C	H	Y	L	V	L	P	S	G	N	Y	L	A	I	S	N	E	L	L	L	T	V	P	T	K	A	I	C	L	N	K	R	K	D	F	T	P	V	Q	V	V	D	S	R	W	N	N	A	R	Q
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T													S	S	S																						S	S															S													T	T	S
	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
Sequence	S	D	N	M	T	A	V	A	C	Q	P	P	Y	C	Y	F	R	N	S	T	T	N	Y	V	G	V	Y	D	I	N	H	G	D	A	G	F	T	S	I	L	S	G	L	L	Y	D	S	P	C	F	S	Q	Q	G	V	F	R	Y	D	N	V	S	S	V	W	P	L	Y	S	Y
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)											T	T	T							S	S								T	T											G	G	G	G	S	B		S				T	T				S		S	S	B		S	S			S	S
	.	.	.	.	.	.	.	.
Sequence	G	R	C	P	T	A	A	D
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		S			B