PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c3c4tA_

Fold library id	PDB Header	Molecule	Title
c3c4tA_	PDB header: hydrolase	Chain: A: PDB Molecule: endoribonuclease dicer;	PDBTitle: structure of rnaseiiib and dsrna binding domains of mouse2 dicer

Links to external resources
Added to library: Tue Mar 16 14:25:01 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence D A E K T L N H L I S G F E T F E K K I N Y R F K N K A Y L L Q A F T H A S Y H Y N T I T D Y Q R L E F L G D A I L D Y L I T K H L Y E D P

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T T T
S S B
S S
T T
S
T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence R Q H S P G V L T D L R S A L V N N T I F A S L A V K Y D Y H K Y F K A V S P E L F H V I D D F V K F Q L E K N E E D I E V P K A M G D I F

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
S
T T G G G S
B
T T
T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence E S L A G A I Y M D S G M S L E V V W Q V Y Y P M M Q P L I E K F S A N V P R S P V R E L L E M E P E T A K F S P A E R T Y D G K V R V T V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T S
T T S
S S S S
T T S

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 .

Sequence E V V G K G K F K G V G R S Y R I A K S A A A R R A L R S L K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T S S T

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	D	A	E	K	T	L	N	H	L	I	S	G	F	E	T	F	E	K	K	I	N	Y	R	F	K	N	K	A	Y	L	L	Q	A	F	T	H	A	S	Y	H	Y	N	T	I	T	D	Y	Q	R	L	E	F	L	G	D	A	I	L	D	Y	L	I	T	K	H	L	Y	E	D	P
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)											T	T								T	T				S	S									B		S	S		T	T			S																										T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	R	Q	H	S	P	G	V	L	T	D	L	R	S	A	L	V	N	N	T	I	F	A	S	L	A	V	K	Y	D	Y	H	K	Y	F	K	A	V	S	P	E	L	F	H	V	I	D	D	F	V	K	F	Q	L	E	K	N	E	E	D	I	E	V	P	K	A	M	G	D	I	F
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T															S												T	T	G	G	G	S		B																				T	T								T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	E	S	L	A	G	A	I	Y	M	D	S	G	M	S	L	E	V	V	W	Q	V	Y	Y	P	M	M	Q	P	L	I	E	K	F	S	A	N	V	P	R	S	P	V	R	E	L	L	E	M	E	P	E	T	A	K	F	S	P	A	E	R	T	Y	D	G	K	V	R	V	T	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)											T	T	S																						T	T	S												S	S	S	S										T	T	S
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.
Sequence	E	V	V	G	K	G	K	F	K	G	V	G	R	S	Y	R	I	A	K	S	A	A	A	R	R	A	L	R	S	L	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			T	T	T								S	S																T