PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c3ah5E_

Fold library id	PDB Header	Molecule	Title
c3ah5E_	PDB header: transferase	Chain: E: PDB Molecule: thymidylate synthase thyx;	PDBTitle: crystal structure of flavin dependent thymidylate synthase thyx from2 helicobacter pylori complexed with fad and dump

Links to external resources
Added to library: Sat Apr 23 08:54:22 2011

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence M E V I C K H Y T P L D I A S Q A I R T C W Q S F E Y S D D G G C K D K E L I H R V G N I F R H S S T L E H L Y Y N F E I K G L S R G A L Q

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
G G G
S S S T S G G G G G G G G G

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence E L S R H R I A S L S V K S S R Y T L R E L K E V E S F L P L N E T N L E R A K E F L V F V D N E K V N A M S V L A L E N L R I L L S E H N

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
S S
G G G G T T
S
T T T B
S
T S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . .

Sequence I K N D L A K Y A M P E S Y K T H L A Y S I N A R S L Q N F L T L R S S N K A L K E M Q D L A K A L F D A L P G E H Q Y L F E D C L K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
G G G
T T B S S T T S
T S
G G G G G G T G G G

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	M	E	V	I	C	K	H	Y	T	P	L	D	I	A	S	Q	A	I	R	T	C	W	Q	S	F	E	Y	S	D	D	G	G	C	K	D	K	E	L	I	H	R	V	G	N	I	F	R	H	S	S	T	L	E	H	L	Y	Y	N	F	E	I	K	G	L	S	R	G	A	L	Q
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)											T												T		G	G	G			S	S	S												T	S	G	G	G	G	G	G	G	G	G
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	E	L	S	R	H	R	I	A	S	L	S	V	K	S	S	R	Y	T	L	R	E	L	K	E	V	E	S	F	L	P	L	N	E	T	N	L	E	R	A	K	E	F	L	V	F	V	D	N	E	K	V	N	A	M	S	V	L	A	L	E	N	L	R	I	L	L	S	E	H	N
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			T	T			S	S											G	G	G	G	T	T						S										T	T	T	B				S																					T	S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.
Sequence	I	K	N	D	L	A	K	Y	A	M	P	E	S	Y	K	T	H	L	A	Y	S	I	N	A	R	S	L	Q	N	F	L	T	L	R	S	S	N	K	A	L	K	E	M	Q	D	L	A	K	A	L	F	D	A	L	P	G	E	H	Q	Y	L	F	E	D	C	L	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)							G	G	G			T	T	B																					S	S	T	T	S														T	S		G	G	G	G	G	G	T	G	G	G