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 Protein Homology/analogY Recognition Engine V 2.0


 

Fold library entry viewer: c2y3aA_

Fold library idPDB HeaderMoleculeTitle
c2y3aA_PDB header: transferaseChain: A: PDB Molecule: phosphatidylinositol-4,5-bisphosphate 3-kinase catalyticPDBTitle: crystal structure of p110beta in complex with icsh2 of p85beta and2 the drug gdc-0941


Added to library: Sat Mar 19 08:50:41 2011
 
Links to external resources


 1........10.........20.........30.........40.........50.........60.........70
Sequence AVDSQIASDGAISVDFLLPTGIYIQLEVPREATISYIKQMLWKQVHNYPMFNLLMDIDSYMFACVNQTAV
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Known secondary structure (DSSP)

SS
SS

S
TT

TT
BGGGSTTTTS


GGGBSSS
 .........80.........90.........100.........110.........120.........130.........140
Sequence YEELEDETRRLCDVRPFLPVLKLVTRSCDPAEKLDSKIGVLIGKGLHEFDALKDPEVNEFRRKMRKFSEA
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Known secondary structure (DSSP)


TTSBSGGG
BSSS
S


SS
STS
TTT

 .........150.........160.........170.........180.........190.........200.........210
Sequence KIQSLVGLSWIDWLKHTYPPEHEPSVLENLEDKLYGGKLVVAVHFENSQDVFSFQVSPNLNPIKINELAI
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Known secondary structure (DSSP)

TTTTS


B
TTGGGTS


SSSS
TT
S


TTS
T
 .........220.........230.........240.........250.........260.........270.........280
Sequence QKRLTASPCDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAIEAAII
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Known secondary structure (DSSP)






GGGTTBS

SSS
GGGBTT


TT


 .........290.........300.........310.........320.........330.........340.........350
Sequence WDNNNPFQITLVKGNKLNTEETVKVHVRAGLFHGTELLCKTVVSSEISGKNDHIWNEQLEFDINICDLPR
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Known secondary structure (DSSP)



S








SS




B

TTSS


B




SSS




SSS

T
 .........360.........370.........380.........390.........400.........410.........420
Sequence MARLCFAVYAVVAWVNTMVFDFKGQLRSGDVILHSWSSFPDELEEMLNPMGTVQTNPYAENATALHITFP
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Known secondary structure (DSSP) T






SB
TT
BB





TT


S

SSS

SS
SS

S

TTS



 .........430.........440.........450.........460.........470.........480.........490
Sequence ENKKQPCYYPPFDKIIEKAAELAGKKFLAVLKEILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLL
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Known secondary structure (DSSP)

SSS

B


TT

TTTTTTS
TTS


T
GGG
 .........500.........510.........520.........530.........540.........550.........560
Sequence LSIKWNKLEDVAQLQALLQIWPKLPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLK
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Known secondary structure (DSSP) S
TT
TS



GGGGSTT


TTSS
 .........570.........580.........590.........600.........610.........620.........630
Sequence YEPFLDCALSRFLLERALDNRRIGQFLFWHLRSEVHTPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALN
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Known secondary structure (DSSP)
SSSS
TS
SSTSTTTT
 .........640.........650.........660.........670.........680.........690.........700
Sequence KLKTLNSLIKLNAVKLSRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPLW
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Known secondary structure (DSSP) S
STTTSSS

SS
SSB





GGG

SSTT

 .........710.........720.........730.........740.........750.........760.........770
Sequence LVYSSRAFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTS
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Known secondary structure (DSSP)
TTTSSS

SS

S










SSS



TT
 .........780.........790.........800.........810.........820.........830.........840
Sequence ETIADIQLNSSNVAATAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGIGDRHSDNIMV
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Known secondary structure (DSSP)
BSSS
TTTTTS
SSTT

TTT




TTT
 .........850.........860.........870.........880.........890.........900.........910
Sequence KKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHG
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Known secondary structure (DSSP)
TTS



S

SS



GGG










TT
SS
SSSTTT
 .........920.........930.........940.........950.........960.........970......
Sequence NLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHT
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Known secondary structure (DSSP) TSTT

SS
SSTT
SS
TS


Download:PDB structure FASTA sequence

Hidden Markov model

Image coloured by rainbow N → C terminus
Interactive 3D view in JSmol


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Please cite: The Phyre2 web portal for protein modeling, prediction and analysis
Kelley LA et al. Nature Protocols 10, 845-858 (2015) [paper] [Citation link]
 
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