PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c2x2iB_

Fold library id	PDB Header	Molecule	Title
c2x2iB_	PDB header: lyase	Chain: B: PDB Molecule: alpha-1,4-glucan lyase isozyme 1;	PDBTitle: crystal structure of the gracilariopsis lemaneiformis alpha-2 1,4-glucan lyase with acarbose

Links to external resources
Added to library: Sat Jan 22 08:59:41 2011

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence T D N P D G I D Y K T Y D Y V G V W G F S P L S N T N W F A A G S S T P G G I T D W T A T M N V N F D R I D N P S I T V Q H P V Q V Q V T S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
B
T T
S
G G G
S T T
T T T T T T
T T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence Y N N N S Y R V R F N P D G P I R D V T R G P I L K Q Q L D W I R T Q E L S E G C D P G M T F T S E G F L T F E T K D L S V I I Y G N F K T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T T
T T S S
S S S S S
T T T
T T
T T
T T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence R V T R K S D G K V I M E N D E V G T A S S G N K C R G L M F V D R L Y G N A I A S V N K N F R N D A V K Q E G F Y G A G E V N C K Y Q D T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T T B
S S S
T T T
T T S T T T
T T
T T

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280

Sequence Y I L E R T G I A M T N Y N Y D N L N Y N Q W D L R P P H H D G A L N P D Y Y I P M Y Y A A P W L I V N G C A G T S E Q Y S Y G W F M D N V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
S
G G G
G G G S
T T
S
T T S
S
S T T S T T

. . . . . . . . . 290 . . . . . . . . . 300 . . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350

Sequence S Q S Y M N T G D T T W N S G Q E D L A Y M G A Q Y G P F D Q H F V Y G A G G G M E V V T A F S L L Q G K E F E N Q V L N K R S V M P P K Y

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
S S
G G G
T T S S
S S S S
T
G G G T
S S
S S S
G G

. . . . . . . . . 360 . . . . . . . . . 370 . . . . . . . . . 380 . . . . . . . . . 390 . . . . . . . . . 400 . . . . . . . . . 410 . . . . . . . . . 420

Sequence V F G F F Q G V F G T S S L L R A H M P A G E N N I S V E E I V E G Y Q N N N F P F E G L A V D V D M Q D N L R V F T T K G E F W T A N R V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) G G S
S S G G G
T T
T T T
G G G S B T T B T T
G G G B T T S S

. . . . . . . . . 430 . . . . . . . . . 440 . . . . . . . . . 450 . . . . . . . . . 460 . . . . . . . . . 470 . . . . . . . . . 480 . . . . . . . . . 490

Sequence G T G G D P N N R S V F E W A H D K G L V C Q T N I T C F L R N D N E G Q D Y E V N Q T L R E R Q L Y T K N D S L T G T D F G M T D D G P S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
T T S
B T T T
S
T T
T T
B
B T T
S S S
T

. . . . . . . . . 500 . . . . . . . . . 510 . . . . . . . . . 520 . . . . . . . . . 530 . . . . . . . . . 540 . . . . . . . . . 550 . . . . . . . . . 560

Sequence D A Y I G H L D Y G G G V E C D A L F P D W G R P D V A E W W G N N Y K K L F S I G L D F V W Q D M T V P A M M P H K I G D D I N V K P D G

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T S
S T T
B
T T S T T T T T T
S T T T
B T T S
T T
T

. . . . . . . . . 570 . . . . . . . . . 580 . . . . . . . . . 590 . . . . . . . . . 600 . . . . . . . . . 610 . . . . . . . . . 620 . . . . . . . . . 630

Sequence N W P N A D D P S N G Q Y N W K T Y H P Q V L V T D M R Y E N H G R E P M V T Q R N I H A Y T L C E S T R K E G I V E N A D T L T K F R R S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
S
S S S
T T
B
S S S S
T T B
S S S T T S
G G G S G G G T T T T T T G G G
S
S

. . . . . . . . . 640 . . . . . . . . . 650 . . . . . . . . . 660 . . . . . . . . . 670 . . . . . . . . . 680 . . . . . . . . . 690 . . . . . . . . . 700

Sequence Y I I S R G G Y I G N Q H F G G M W V G D N S T T S N Y I Q M M I A N N I N M N M S C L P L V G S D I G G F T S Y D N E N Q R T P C T G D L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
T T G G G S
S
B S S T T
S
B T T
S B
S S
T T

. . . . . . . . . 710 . . . . . . . . . 720 . . . . . . . . . 730 . . . . . . . . . 740 . . . . . . . . . 750 . . . . . . . . . 760 . . . . . . . . . 770

Sequence M V R Y V Q A G C L L P W F R N H Y D R W I E S K D H G K D Y Q E L Y M Y P N E M D T L R K F V E F R Y R W Q E V L Y T A M Y Q N A A F G K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T S S
B
B T T B
S B S
G G G
S T T T

. . . . . . . . . 780 . . . . . . . . . 790 . . . . . . . . . 800 . . . . . . . . . 810 . . . . . . . . . 820 . . . . . . . . . 830 . . . . . . . . . 840

Sequence P I I K A A S M Y N N D S N V R R A Q N D H F L L G G H D G Y R I L C A P V V W E N S T E R E L Y L P V L T Q W Y K F G P D F D T K P L E G

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S G G G S T T
S S T T T
T T T S
S
S S S
S S S
S G G G G S S

. . . . . . . . . 850 . . . . . . . . . 860 . . . . . . . . . 870 . . . . . . . . . 880 . . . . . . . . . 890 . . . . . . . . . 900 . . . . . . . . . 910

Sequence A M N G G D R I Y N Y P V P Q S E S P I F V R E G A I L P T R Y T L N G E N K S L N T Y T D E D P L V F E V F P L G N N R A D G M C Y L D D

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
T T
S S
T T S
G G G
T T S
S
B T T

. . . . . . . . . 920 . . . . . . . . . 930 . . . . . . . . . 940 . . . . . . . . . 950 . . . . . . . . . 960 . . . . . . . . . 970 . . . . . . . . . 980

Sequence G G V T T N A E D N G K F S V V K V A A E Q D G G T E T I T F T N D C Y E Y V F G G P F Y V R V R G A Q S P S N I H V S S G A G S Q D M K V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T S
T
T T S S
S
T T
S
T T

. . . . . . . . . 990 . . . . . . . . . 1000 . . . . . . . . . 1010 . . . . . . . . . 1020 . . . .

Sequence S S A T S R A A L F N D G E N G D F W V D Q E T D S L W L K L P N V V L P D A V I T I T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
S T
T T G G G T
G G G T T T

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	T	D	N	P	D	G	I	D	Y	K	T	Y	D	Y	V	G	V	W	G	F	S	P	L	S	N	T	N	W	F	A	A	G	S	S	T	P	G	G	I	T	D	W	T	A	T	M	N	V	N	F	D	R	I	D	N	P	S	I	T	V	Q	H	P	V	Q	V	Q	V	T	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		B		T	T								S				G	G	G			S	T	T		T	T														T	T											T	T		T	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	Y	N	N	N	S	Y	R	V	R	F	N	P	D	G	P	I	R	D	V	T	R	G	P	I	L	K	Q	Q	L	D	W	I	R	T	Q	E	L	S	E	G	C	D	P	G	M	T	F	T	S	E	G	F	L	T	F	E	T	K	D	L	S	V	I	I	Y	G	N	F	K	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T	T	T								T	T	S	S					S	S	S	S	S														T	T	T									T	T								T	T							T	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	R	V	T	R	K	S	D	G	K	V	I	M	E	N	D	E	V	G	T	A	S	S	G	N	K	C	R	G	L	M	F	V	D	R	L	Y	G	N	A	I	A	S	V	N	K	N	F	R	N	D	A	V	K	Q	E	G	F	Y	G	A	G	E	V	N	C	K	Y	Q	D	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)					T	T	T	T						B						S	S	S												T	T	T												T	T	S	T	T	T								T	T						T	T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Sequence	Y	I	L	E	R	T	G	I	A	M	T	N	Y	N	Y	D	N	L	N	Y	N	Q	W	D	L	R	P	P	H	H	D	G	A	L	N	P	D	Y	Y	I	P	M	Y	Y	A	A	P	W	L	I	V	N	G	C	A	G	T	S	E	Q	Y	S	Y	G	W	F	M	D	N	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			S				S											G	G	G			G	G	G	S		T	T			S						T	T	S			S											S	T	T	S	T	T
	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
Sequence	S	Q	S	Y	M	N	T	G	D	T	T	W	N	S	G	Q	E	D	L	A	Y	M	G	A	Q	Y	G	P	F	D	Q	H	F	V	Y	G	A	G	G	G	M	E	V	V	T	A	F	S	L	L	Q	G	K	E	F	E	N	Q	V	L	N	K	R	S	V	M	P	P	K	Y
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S						S	S			G	G	G				T	T							S	S											S	S	S	S											T			G	G	G	T		S	S		S	S	S					G	G
	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence	V	F	G	F	F	Q	G	V	F	G	T	S	S	L	L	R	A	H	M	P	A	G	E	N	N	I	S	V	E	E	I	V	E	G	Y	Q	N	N	N	F	P	F	E	G	L	A	V	D	V	D	M	Q	D	N	L	R	V	F	T	T	K	G	E	F	W	T	A	N	R	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	G	G	S											S	S	G	G	G					T	T													T	T	T										G	G	G	S	B	T	T	B	T	T				G	G	G	B	T	T	S	S
	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490
Sequence	G	T	G	G	D	P	N	N	R	S	V	F	E	W	A	H	D	K	G	L	V	C	Q	T	N	I	T	C	F	L	R	N	D	N	E	G	Q	D	Y	E	V	N	Q	T	L	R	E	R	Q	L	Y	T	K	N	D	S	L	T	G	T	D	F	G	M	T	D	D	G	P	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			S			T	T	S		B							T	T	T									S							T	T												T	T		B					B	T	T								S	S	S		T
	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560
Sequence	D	A	Y	I	G	H	L	D	Y	G	G	G	V	E	C	D	A	L	F	P	D	W	G	R	P	D	V	A	E	W	W	G	N	N	Y	K	K	L	F	S	I	G	L	D	F	V	W	Q	D	M	T	V	P	A	M	M	P	H	K	I	G	D	D	I	N	V	K	P	D	G
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	S								S	T	T								B		T	T	S	T	T									T					T	T	T								S	T	T	T						B	T	T	S		T	T					T
	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630
Sequence	N	W	P	N	A	D	D	P	S	N	G	Q	Y	N	W	K	T	Y	H	P	Q	V	L	V	T	D	M	R	Y	E	N	H	G	R	E	P	M	V	T	Q	R	N	I	H	A	Y	T	L	C	E	S	T	R	K	E	G	I	V	E	N	A	D	T	L	T	K	F	R	R	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T		S		S	S	S			T	T		B		S	S	S	S		T	T	B					S	S	S	T	T	S					G	G	G	S	G	G	G												T	T	T	T	T	T	G	G	G			S		S
	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700
Sequence	Y	I	I	S	R	G	G	Y	I	G	N	Q	H	F	G	G	M	W	V	G	D	N	S	T	T	S	N	Y	I	Q	M	M	I	A	N	N	I	N	M	N	M	S	C	L	P	L	V	G	S	D	I	G	G	F	T	S	Y	D	N	E	N	Q	R	T	P	C	T	G	D	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)					S				T	T	G	G	G	S							S		B	S	S																	T	T			S				B	T	T		S	B				S	S		T	T
	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770
Sequence	M	V	R	Y	V	Q	A	G	C	L	L	P	W	F	R	N	H	Y	D	R	W	I	E	S	K	D	H	G	K	D	Y	Q	E	L	Y	M	Y	P	N	E	M	D	T	L	R	K	F	V	E	F	R	Y	R	W	Q	E	V	L	Y	T	A	M	Y	Q	N	A	A	F	G	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)									T	T	S	S								B		B	T	T	B			S	B	S				G	G	G		S	T	T														T
	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840
Sequence	P	I	I	K	A	A	S	M	Y	N	N	D	S	N	V	R	R	A	Q	N	D	H	F	L	L	G	G	H	D	G	Y	R	I	L	C	A	P	V	V	W	E	N	S	T	E	R	E	L	Y	L	P	V	L	T	Q	W	Y	K	F	G	P	D	F	D	T	K	P	L	E	G
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		S	S			G	G	G	S	T	T		S	S					T	T	T						T	T	T	S		S								S	S	S										S	S	S						S	G	G	G	G	S	S
	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910
Sequence	A	M	N	G	G	D	R	I	Y	N	Y	P	V	P	Q	S	E	S	P	I	F	V	R	E	G	A	I	L	P	T	R	Y	T	L	N	G	E	N	K	S	L	N	T	Y	T	D	E	D	P	L	V	F	E	V	F	P	L	G	N	N	R	A	D	G	M	C	Y	L	D	D
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				T	T										T	T								S	S									T	T	S					G	G	G			T	T	S								S		B	T	T
	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980
Sequence	G	G	V	T	T	N	A	E	D	N	G	K	F	S	V	V	K	V	A	A	E	Q	D	G	G	T	E	T	I	T	F	T	N	D	C	Y	E	Y	V	F	G	G	P	F	Y	V	R	V	R	G	A	Q	S	P	S	N	I	H	V	S	S	G	A	G	S	Q	D	M	K	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T	S		T																			T	T												S	S				S							T	T					S							T	T
	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.	.	.	.
Sequence	S	S	A	T	S	R	A	A	L	F	N	D	G	E	N	G	D	F	W	V	D	Q	E	T	D	S	L	W	L	K	L	P	N	V	V	L	P	D	A	V	I	T	I	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		S			S							T			T	T						G	G	G	T								G	G	G	T	T	T