PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c2w9zA_

Fold library id	PDB Header	Molecule	Title
c2w9zA_	PDB header: transferase	Chain: A: PDB Molecule: g1/s-specific cyclin-d1;	PDBTitle: crystal structure of cdk4 in complex with a d-type cyclin

Links to external resources
Added to library: Tue Mar 16 13:59:16 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence L L N D R V L R A M L K A E E T C A P S V S Y F K C V Q K E V L P S M R K I V A T W M L E V C E E Q K C E E E V F P L A M N Y L D R F L S L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
T T T
S S
T T
T T T T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence E P V K K S R L Q L L G A T C M F V A S K M K E T I P L T A E K L C I Y T D N S I R P E E L L Q M E L L L V N K L K W N L A A M T P H D F I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
G G G
S S
T T T S S
T T T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence E H F L S K M P E A E E N K Q I I R K H A Q T F V A L C A T D V K F I S N P P S M V A A G S V V A A V Q G L N L R S P N N F L S Y Y R L T R

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T S
T S T S
S T T T
G G G T T

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . .

Sequence F L S R V I K C D P D C L R A C Q E Q I E A L L E S S L R Q A Q Q N M D

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T S

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	L	L	N	D	R	V	L	R	A	M	L	K	A	E	E	T	C	A	P	S	V	S	Y	F	K	C	V	Q	K	E	V	L	P	S	M	R	K	I	V	A	T	W	M	L	E	V	C	E	E	Q	K	C	E	E	E	V	F	P	L	A	M	N	Y	L	D	R	F	L	S	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																T	T				T	T					T		S	S																				T	T			T	T														T	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	E	P	V	K	K	S	R	L	Q	L	L	G	A	T	C	M	F	V	A	S	K	M	K	E	T	I	P	L	T	A	E	K	L	C	I	Y	T	D	N	S	I	R	P	E	E	L	L	Q	M	E	L	L	L	V	N	K	L	K	W	N	L	A	A	M	T	P	H	D	F	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S				G	G	G																		S	S											T	T	T	S	S																T	T	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	E	H	F	L	S	K	M	P	E	A	E	E	N	K	Q	I	I	R	K	H	A	Q	T	F	V	A	L	C	A	T	D	V	K	F	I	S	N	P	P	S	M	V	A	A	G	S	V	V	A	A	V	Q	G	L	N	L	R	S	P	N	N	F	L	S	Y	Y	R	L	T	R
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						T	S																							T	S	T					S																					S	T	T	T		G	G	G	T	T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.
Sequence	F	L	S	R	V	I	K	C	D	P	D	C	L	R	A	C	Q	E	Q	I	E	A	L	L	E	S	S	L	R	Q	A	Q	Q	N	M	D
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						T	T	S