PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c2vsgB_

Fold library id	PDB Header	Molecule	Title
c2vsgB_	PDB header: membrane protein	Chain: B: PDB Molecule: variant surface glycoprotein iltat 1.24;	PDBTitle: a structural motif in the variant surface glycoproteins of2 trypanosoma brucei

Links to external resources
Added to library: Tue Mar 16 13:17:28 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence T H F G V K Y E L W Q P E C E L T A E L R K T A G V A K M K V N S D L N S F K T L E L T K M K L L T F A A K F P E S K E A L T L R A L E A A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
B
T T S T T S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence L N T D L R A L R D N I A N G I D R A V R A T A Y A S E A A G A L F S G I Q T L H D A T D G T T Y C L S A S G Q G S N G N A A M A S Q G C K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S B
S S
B S B
S T T
S
T T T T G G G T
S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence P L A L P E L L T E D S Y N T D V I S D K G F P K I S P L T N A Q G Q G K S G E C G L F Q A A S G A Q A T N T G V Q F S G G S R I N L G L G

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S
T T T S
S S S
T T
B
S S S S B
S S S
T T S
S S
T T T S S S
S S
T T T

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280

Sequence A I V A S A A Q Q P T R P D L S D F S G T A R N Q A D T L Y G K A H A S I T E L L Q L A Q G P K P G Q T E V E T M K L L A Q K T A A L D S I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T S S T T
B B
S
T T T T T G G G G G S T
S S T S

. . . . . . . . . 290 . . . . . . . . . 300 . . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350

Sequence K F Q L A A S T G K K T S D Y K E D E N L K T E Y F G K T E S N I E A L W N K V K E E K V K G A D P E D P S K E S K I S D L N T E E Q L Q R

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
G G G
T
G G G
S S S
T T
G G G

. . . . . . . .

Sequence V L D Y Y A V A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	T	H	F	G	V	K	Y	E	L	W	Q	P	E	C	E	L	T	A	E	L	R	K	T	A	G	V	A	K	M	K	V	N	S	D	L	N	S	F	K	T	L	E	L	T	K	M	K	L	L	T	F	A	A	K	F	P	E	S	K	E	A	L	T	L	R	A	L	E	A	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)					B																T	T																																	S	T	T	S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	L	N	T	D	L	R	A	L	R	D	N	I	A	N	G	I	D	R	A	V	R	A	T	A	Y	A	S	E	A	A	G	A	L	F	S	G	I	Q	T	L	H	D	A	T	D	G	T	T	Y	C	L	S	A	S	G	Q	G	S	N	G	N	A	A	M	A	S	Q	G	C	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																																											S	B		S	S		B	S	B			S	T	T		S			T	T	T	T	G	G	G	T		S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	P	L	A	L	P	E	L	L	T	E	D	S	Y	N	T	D	V	I	S	D	K	G	F	P	K	I	S	P	L	T	N	A	Q	G	Q	G	K	S	G	E	C	G	L	F	Q	A	A	S	G	A	Q	A	T	N	T	G	V	Q	F	S	G	G	S	R	I	N	L	G	L	G
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						S	S								T	T	T	S		S	S	S		T	T				B		S	S	S	S	B			S	S	S			T	T	S			S	S		T	T	T	S	S	S					S	S						T	T	T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Sequence	A	I	V	A	S	A	A	Q	Q	P	T	R	P	D	L	S	D	F	S	G	T	A	R	N	Q	A	D	T	L	Y	G	K	A	H	A	S	I	T	E	L	L	Q	L	A	Q	G	P	K	P	G	Q	T	E	V	E	T	M	K	L	L	A	Q	K	T	A	A	L	D	S	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T				S	S	T	T			B	B				S		T	T	T	T	T	G	G	G	G	G	S														T									S	S										T	S
	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
Sequence	K	F	Q	L	A	A	S	T	G	K	K	T	S	D	Y	K	E	D	E	N	L	K	T	E	Y	F	G	K	T	E	S	N	I	E	A	L	W	N	K	V	K	E	E	K	V	K	G	A	D	P	E	D	P	S	K	E	S	K	I	S	D	L	N	T	E	E	Q	L	Q	R
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)								T	T			G	G	G												T		G	G	G																			S	S	S		T	T					G	G	G
	.	.	.	.	.	.	.	.
Sequence	V	L	D	Y	Y	A	V	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)