PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c2v9pH_

Fold library id	PDB Header	Molecule	Title
c2v9pH_	PDB header: hydrolase	Chain: H: PDB Molecule: replication protein e1;	PDBTitle: crystal structure of papillomavirus e1 hexameric helicase2 dna-free form

Links to external resources
Added to library: Tue Mar 16 13:41:14 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence T L N E S K F D F G T M V Q W A Y D H K Y A E E S K I A Y E Y A L A A G S D S N A R A F L A T N S Q A K H V K D C A T M V R H Y L R A E T Q

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
T T S
T T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence A L S M P A Y I K A R C K L A T G E G S W K S I L T F F N Y Q N I E L I T F I N A L K L W L K G I P K K N C L A F I G P P N T G K S M L C N

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
S S
T T
T
T T
S
S S S S S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence S L I H F L G G S V L S F A N H K S H F W L A S L A D T R A A L V D D A T H A C W R Y F D T Y L R N A L D G Y P V S I D R K H K A A V Q I K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
G G G T T S T T T T G G G G T
S
S
T T
S S S

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . .

Sequence A P P L L V T S N I D V Q A E D R Y L Y L H S R V Q T F R F E Q P C T P F N I T D A D W K S F F V R L W G R L D L I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S
G G G
G G G G G G T T T
S
T T T T T T

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	T	L	N	E	S	K	F	D	F	G	T	M	V	Q	W	A	Y	D	H	K	Y	A	E	E	S	K	I	A	Y	E	Y	A	L	A	A	G	S	D	S	N	A	R	A	F	L	A	T	N	S	Q	A	K	H	V	K	D	C	A	T	M	V	R	H	Y	L	R	A	E	T	Q
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																			T	T															T	T	S											T	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	A	L	S	M	P	A	Y	I	K	A	R	C	K	L	A	T	G	E	G	S	W	K	S	I	L	T	F	F	N	Y	Q	N	I	E	L	I	T	F	I	N	A	L	K	L	W	L	K	G	I	P	K	K	N	C	L	A	F	I	G	P	P	N	T	G	K	S	M	L	C	N
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		S															S	S													T	T																T		T	T		S							S	S	S	S	S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	S	L	I	H	F	L	G	G	S	V	L	S	F	A	N	H	K	S	H	F	W	L	A	S	L	A	D	T	R	A	A	L	V	D	D	A	T	H	A	C	W	R	Y	F	D	T	Y	L	R	N	A	L	D	G	Y	P	V	S	I	D	R	K	H	K	A	A	V	Q	I	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)							T						G	G	G	T	T	S	T	T	T	T	G	G	G	G	T		S						S																		T	T								S	S	S
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.
Sequence	A	P	P	L	L	V	T	S	N	I	D	V	Q	A	E	D	R	Y	L	Y	L	H	S	R	V	Q	T	F	R	F	E	Q	P	C	T	P	F	N	I	T	D	A	D	W	K	S	F	F	V	R	L	W	G	R	L	D	L	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)									S	S		G	G	G		G	G	G	G	G	G	T	T	T								S																			T	T	T	T	T	T