PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c2r4gA_

Fold library id	PDB Header	Molecule	Title
c2r4gA_	PDB header: transferase	Chain: A: PDB Molecule: telomerase reverse transcriptase;	PDBTitle: the high resolution structure of the rna-binding domain of2 telomerase

Links to external resources
Added to library: Tue Mar 16 13:22:34 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence K V I Q E K L K P D H P Q T I I K K T L L K E Y Q S K N F S C Q E E R D L F L E F T E K I V Q N F H N I N F N Y L L K K F C K L P E N Y Q S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
S
S S
S
T T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence L K S Q V K Q I V Q S E N K A N Q Q S C E N L F N S L Y D T E I S Y K Q I T N F L R Q I I Q N C V P N Q L L G K K N F K V F L E K L Y E F V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
S S
G G G
S
G G G T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence Q M K R F E N Q K V L D Y I C F M D V F D V E W F V D L K N Q K F T Q K R K Y I S D K R K I L G D L I V F I I N K I V I P V L R Y N F Y I T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
T T
G G G
S S
T T S
T T T
T

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250

Sequence E K H K E G S Q I F Y Y R K P I W K L V S K L T I V K L E E E N L E K V E E K L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S S T T S
T T T T T T T S

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	K	V	I	Q	E	K	L	K	P	D	H	P	Q	T	I	I	K	K	T	L	L	K	E	Y	Q	S	K	N	F	S	C	Q	E	E	R	D	L	F	L	E	F	T	E	K	I	V	Q	N	F	H	N	I	N	F	N	Y	L	L	K	K	F	C	K	L	P	E	N	Y	Q	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																									S		S			S	S																															S				T	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	L	K	S	Q	V	K	Q	I	V	Q	S	E	N	K	A	N	Q	Q	S	C	E	N	L	F	N	S	L	Y	D	T	E	I	S	Y	K	Q	I	T	N	F	L	R	Q	I	I	Q	N	C	V	P	N	Q	L	L	G	K	K	N	F	K	V	F	L	E	K	L	Y	E	F	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)										S			S	S														G	G	G																			S		G	G	G	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	Q	M	K	R	F	E	N	Q	K	V	L	D	Y	I	C	F	M	D	V	F	D	V	E	W	F	V	D	L	K	N	Q	K	F	T	Q	K	R	K	Y	I	S	D	K	R	K	I	L	G	D	L	I	V	F	I	I	N	K	I	V	I	P	V	L	R	Y	N	F	Y	I	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				T	T										T	T			G	G	G		S	S				T	T	S		T	T	T																								T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250
Sequence	E	K	H	K	E	G	S	Q	I	F	Y	Y	R	K	P	I	W	K	L	V	S	K	L	T	I	V	K	L	E	E	E	N	L	E	K	V	E	E	K	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		S	S	S	T	T	S																								T	T	T	T	T	T	T	S