PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c2pnqA_

Fold library id	PDB Header	Molecule	Title
c2pnqA_	PDB header: hydrolase	Chain: A: PDB Molecule: [pyruvate dehydrogenase [lipoamide]]-phosphatase	PDBTitle: crystal structure of pyruvate dehydrogenase phosphatase 12 (pdp1)

Links to external resources
Added to library: Tue Mar 16 14:11:32 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence L T P P Q V N S I L K A N E Y S F K V P E F D G K N V S S I L G F D S N R L P A N A P I E D R R S A T T C L Q T R G M L L G V F D G H A G C

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T T
S
S S S
S S S S
S S S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence A C S Q A V S E R L F Y Y I A V S L L P H E T L L E I E N A V E L L P I L Q W H K H P N D Y F S K E A S K L Y F N G L R T Y W Q E L I D L D

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T T
T T
S T T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence I D V K E A L I N A F K R L D N D I S L E A Q V G D P N S F L N Y L V L R V A F S G A T A C V A H V D G V D L H V A N T G D S R A M L G V Q

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S S
T T S S

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280

Sequence E E D G S W S A V T L S N D H N A Q N E R E L Q R L K L E H P K N E A K S V V K Q D R L L G L L M P F R A F G D V K F K W S I D L Q K R V I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T S
S T T
T S
G G G B S S S S B T T T B S S S B
G G G T S

. . . . . . . . . 290 . . . . . . . . . 300 . . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350

Sequence E S G P D P P N Y H T P P Y L T A E P E V T Y H R L R P Q D K F L V L A T D G L W E T M H R Q D V V R I V G E Y L T G M H H Q Q Q N A A T H

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S S
T T
S S S
B
T T
T T S
T T
S S

. . . . . . . . . 360 . . . . . . . . . 370 . . . . . . . . . 380 . .

Sequence L I R H A V G Y R D D I T I I V V Q F N S H V V G A Y Q N Q E Q

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
T T

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	L	T	P	P	Q	V	N	S	I	L	K	A	N	E	Y	S	F	K	V	P	E	F	D	G	K	N	V	S	S	I	L	G	F	D	S	N	R	L	P	A	N	A	P	I	E	D	R	R	S	A	T	T	C	L	Q	T	R	G	M	L	L	G	V	F	D	G	H	A	G	C
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																							T	T	T				S												S	S	S											S	S	S	S											S	S	S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	A	C	S	Q	A	V	S	E	R	L	F	Y	Y	I	A	V	S	L	L	P	H	E	T	L	L	E	I	E	N	A	V	E	L	L	P	I	L	Q	W	H	K	H	P	N	D	Y	F	S	K	E	A	S	K	L	Y	F	N	G	L	R	T	Y	W	Q	E	L	I	D	L	D
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																													T	T	T												T	T					S	T	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	I	D	V	K	E	A	L	I	N	A	F	K	R	L	D	N	D	I	S	L	E	A	Q	V	G	D	P	N	S	F	L	N	Y	L	V	L	R	V	A	F	S	G	A	T	A	C	V	A	H	V	D	G	V	D	L	H	V	A	N	T	G	D	S	R	A	M	L	G	V	Q
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																											S	S													S											T	T								S	S
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Sequence	E	E	D	G	S	W	S	A	V	T	L	S	N	D	H	N	A	Q	N	E	R	E	L	Q	R	L	K	L	E	H	P	K	N	E	A	K	S	V	V	K	Q	D	R	L	L	G	L	L	M	P	F	R	A	F	G	D	V	K	F	K	W	S	I	D	L	Q	K	R	V	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		T	T	S												S	T	T											T	S		G	G	G					B	S	S	S	S	B	T	T	T	B	S	S	S	B					G	G	G	T	S
	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
Sequence	E	S	G	P	D	P	P	N	Y	H	T	P	P	Y	L	T	A	E	P	E	V	T	Y	H	R	L	R	P	Q	D	K	F	L	V	L	A	T	D	G	L	W	E	T	M	H	R	Q	D	V	V	R	I	V	G	E	Y	L	T	G	M	H	H	Q	Q	Q	N	A	A	T	H
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S	S	S				T	T		S	S	S				B												T	T													T	T	S														T	T		S	S
	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.
Sequence	L	I	R	H	A	V	G	Y	R	D	D	I	T	I	I	V	V	Q	F	N	S	H	V	V	G	A	Y	Q	N	Q	E	Q
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)										S																				T	T