PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c2p2wA_

Fold library id	PDB Header	Molecule	Title
c2p2wA_	PDB header: transferase	Chain: A: PDB Molecule: citrate synthase;	PDBTitle: crystal structure of citrate synthase from thermotoga2 maritima msb8

Links to external resources
Added to library: Tue Mar 16 12:41:04 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence M I Q K G L E G V K I C E S S I C Y L D G I N G R L Y Y R G I P V E E L A E K S T F E E T A Y F L W Y G K L P T K S E L E E F K R K M A D Y

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
T T
S S T T T T T T
S S
T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence R E L P A E A L G I L Y H L P K N L H Y I D V L K I F L S I H E D L R E K A I R V A S V F P T I L A Y Y Y R Y S K G K E L I R P R K D L S H

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T S
S
S
T T
T T S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence V E N F Y Y M M F G E R N E K I R L L E S A F I L L M E Q D I N A S T F A A L V I A S T L S D L Y S C I V G A L G A L K G P L H G G A S E K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
T T S
S S
T T T
S T T T T T

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280

Sequence V P P M L E E I G S E D R V E E F V Q K C L K E K R K I M G F G H R V Y K T Y D P R A V F L K R V L Q E H F P D S K L F R I A S K L E E Y I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S G G G T
T T B
S S
S S
T T

. . . . . . . . . 290 . . . . . . . . . 300 . . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350

Sequence V S N K I K N I Y P N V D L Y S S V L F E E L G F P R N M F T A L F A T A R V V G W T A H V I E Y V S D N K L I R P T S E Y V G P M D V E Y

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T G G G
B
T T
G G G T T
S
S

. . . . . . . .

Sequence I P I E R R D E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
G G G S

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	M	I	Q	K	G	L	E	G	V	K	I	C	E	S	S	I	C	Y	L	D	G	I	N	G	R	L	Y	Y	R	G	I	P	V	E	E	L	A	E	K	S	T	F	E	E	T	A	Y	F	L	W	Y	G	K	L	P	T	K	S	E	L	E	E	F	K	R	K	M	A	D	Y
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				T	T		T	T							S	S					T	T	T	T					T	T																						S	S																	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	R	E	L	P	A	E	A	L	G	I	L	Y	H	L	P	K	N	L	H	Y	I	D	V	L	K	I	F	L	S	I	H	E	D	L	R	E	K	A	I	R	V	A	S	V	F	P	T	I	L	A	Y	Y	Y	R	Y	S	K	G	K	E	L	I	R	P	R	K	D	L	S	H
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)												T	T	S		S													S																												T	T								T	T	S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	V	E	N	F	Y	Y	M	M	F	G	E	R	N	E	K	I	R	L	L	E	S	A	F	I	L	L	M	E	Q	D	I	N	A	S	T	F	A	A	L	V	I	A	S	T	L	S	D	L	Y	S	C	I	V	G	A	L	G	A	L	K	G	P	L	H	G	G	A	S	E	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)										S				T	T												S			S	S												T	T	T																S	T	T	T	T	T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Sequence	V	P	P	M	L	E	E	I	G	S	E	D	R	V	E	E	F	V	Q	K	C	L	K	E	K	R	K	I	M	G	F	G	H	R	V	Y	K	T	Y	D	P	R	A	V	F	L	K	R	V	L	Q	E	H	F	P	D	S	K	L	F	R	I	A	S	K	L	E	E	Y	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)										S	G	G	G												T				T	T	B			S	S		S	S																	T	T
	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
Sequence	V	S	N	K	I	K	N	I	Y	P	N	V	D	L	Y	S	S	V	L	F	E	E	L	G	F	P	R	N	M	F	T	A	L	F	A	T	A	R	V	V	G	W	T	A	H	V	I	E	Y	V	S	D	N	K	L	I	R	P	T	S	E	Y	V	G	P	M	D	V	E	Y
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			T	T	G	G	G			B													T	T			G	G	G																						T	T												S			S
	.	.	.	.	.	.	.	.
Sequence	I	P	I	E	R	R	D	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			G	G	G	S