PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c2hw5F_

Fold library id	PDB Header	Molecule	Title
c2hw5F_	PDB header: lyase	Chain: F: PDB Molecule: enoyl-coa hydratase;	PDBTitle: the crystal structure of human enoyl-coenzyme a (coa)2 hydratase short chain 1, echs1

Links to external resources
Added to library: Tue Mar 16 14:20:16 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence A N F E Y I I A E K R G K N N T V G L I Q L N R P K A L N A L C D G L I D E L N Q A L K I F E E D P A V G A I V L T G G D K A F A A G A D I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S S G G G
G G G T T
B
T T
S S
B

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence K E M Q N L S F Q D C Y S S K F L K H W D H L T Q V K K P V I A A V N G Y A F G G G C E L A M M C D I I Y A G E K A Q F A Q P E I L I G T I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
T T T T
G G G G G G G
S S
S T T S S T T
G G G G G T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence P G A G G T Q R L T R A V G K S L A M E M V L T G D R I S A Q D A K Q A G L V S K I C P V E T L V E E A I Q C A E K I A S N S K I V V A M A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S
T T S S S
G G G S

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260

Sequence K E S V N A A F E M T L T E G S K L E K K L F Y S T F A T D D R K E G M T A F V E K R K A N F K D Q

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) G G G T S
G G G S T T S

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

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Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	A	N	F	E	Y	I	I	A	E	K	R	G	K	N	N	T	V	G	L	I	Q	L	N	R	P	K	A	L	N	A	L	C	D	G	L	I	D	E	L	N	Q	A	L	K	I	F	E	E	D	P	A	V	G	A	I	V	L	T	G	G	D	K	A	F	A	A	G	A	D	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				S	S							S	G	G	G										G	G	G	T	T		B																			T	T										S	S						B
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	K	E	M	Q	N	L	S	F	Q	D	C	Y	S	S	K	F	L	K	H	W	D	H	L	T	Q	V	K	K	P	V	I	A	A	V	N	G	Y	A	F	G	G	G	C	E	L	A	M	M	C	D	I	I	Y	A	G	E	K	A	Q	F	A	Q	P	E	I	L	I	G	T	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				T	T									T	T	T	T		G	G	G	G	G	G	G		S	S								S				T								T	S	S						T	T						G	G	G	G	G	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	P	G	A	G	G	T	Q	R	L	T	R	A	V	G	K	S	L	A	M	E	M	V	L	T	G	D	R	I	S	A	Q	D	A	K	Q	A	G	L	V	S	K	I	C	P	V	E	T	L	V	E	E	A	I	Q	C	A	E	K	I	A	S	N	S	K	I	V	V	A	M	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			S	S																																T	T	S	S	S					G	G	G															S
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260
Sequence	K	E	S	V	N	A	A	F	E	M	T	L	T	E	G	S	K	L	E	K	K	L	F	Y	S	T	F	A	T	D	D	R	K	E	G	M	T	A	F	V	E	K	R	K	A	N	F	K	D	Q
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						G	G	G	T	S																G	G	G	S												T	T	S