PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c2gpqA_

Fold library id	PDB Header	Molecule	Title
c2gpqA_	PDB header: translation	Chain: A: PDB Molecule: eukaryotic translation initiation factor 4e;	PDBTitle: cap-free structure of eif4e suggests basis for its2 allosteric regulation

Links to external resources
Added to library: Wed Jan 9 16:12:07 2013

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence M A T V E P E T T P T P N P P T T E E E K T E S N Q E V A N P E H Y I K H P L Q N R W A L W F F K N D K S K T W Q A N L R L I S K F D T V E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
S
S S
S
S S S S
S S
T T S
T T T S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence D F W A L Y N H I Q L S S N L M P G C D Y S L F K D G I E P M W E D E K N K R G G R W L I T L N K Q Q R R S D L D R F W L E T L L C L I G E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T T S
T T T T
S S S S
T S G G G T T T S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence S F D D Y S D D V C G A V V N V R A K G D K I A I W T T E C E N R E A V T H I G R V Y K E R L G L P P K I V I G Y Q S H A D T A T K S G S T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S G G G G G G T T S
T T
T T T T T
G G G G G T
S S

. . . . . . .

Sequence T K N R F V V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S S S B

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	M	A	T	V	E	P	E	T	T	P	T	P	N	P	P	T	T	E	E	E	K	T	E	S	N	Q	E	V	A	N	P	E	H	Y	I	K	H	P	L	Q	N	R	W	A	L	W	F	F	K	N	D	K	S	K	T	W	Q	A	N	L	R	L	I	S	K	F	D	T	V	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						S									S				S	S		S						S	S	S	S		S	S																		T	T	S		T	T	T	S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	D	F	W	A	L	Y	N	H	I	Q	L	S	S	N	L	M	P	G	C	D	Y	S	L	F	K	D	G	I	E	P	M	W	E	D	E	K	N	K	R	G	G	R	W	L	I	T	L	N	K	Q	Q	R	R	S	D	L	D	R	F	W	L	E	T	L	L	C	L	I	G	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)										T	T	T	T	S			T	T								T	T			S	S	S	S		T					S									G	G	G	T	T	T																S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	S	F	D	D	Y	S	D	D	V	C	G	A	V	V	N	V	R	A	K	G	D	K	I	A	I	W	T	T	E	C	E	N	R	E	A	V	T	H	I	G	R	V	Y	K	E	R	L	G	L	P	P	K	I	V	I	G	Y	Q	S	H	A	D	T	A	T	K	S	G	S	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S	S	G	G	G	G	G	G										T	T									S		T	T																	T	T	T	T	T								G	G	G	G	G	T		S	S
	.	.	.	.	.	.	.
Sequence	T	K	N	R	F	V	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S	S	S	S	B