PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c2gkiA_

Fold library id	PDB Header	Molecule	Title
c2gkiA_	PDB header: immune system	Chain: A: PDB Molecule: nuclease;	PDBTitle: heavy and light chain variable single domains of an anti-2 dna binding antibody hydrolyze both double- and single-3 stranded dnas without sequence specificity

Links to external resources
Added to library: Tue Mar 16 13:30:23 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence E V Q L Q Q S G P E L V K P G A S V K M S C K A S G Y T F T S Y V M H W V K Q K P G Q G L E W I G Y I N P Y N D G T K Y N E K F K G K A T L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
S S
G G G S
T T S
T T T T
G G G B T T B

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence T S D K S S S T A Y M E L S S L T S E D S A V Y Y C A R G A Y K R G Y A M D Y W G Q G T S V T V S S D L V M S Q S P S S L A V S A G E K V T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) G G G T
S
G G G
G G G T T
S
S T T S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence M S C K S S Q S L F N S R T R K N Y L A W Y Q Q K P G Q S P K L L I Y W A S T R E S G V P D R F T G S G S G T D F T L T I S S V Q A E D L A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S
T T T T
T T S
T T T
T T
T T T T S S
G G G

. . . . . . . . . 220 . . . . . . . . . 230 . . . . .

Sequence V Y Y C K Q S Y Y H M Y T F G S G T K L E I K H H

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

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Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	E	V	Q	L	Q	Q	S	G	P	E	L	V	K	P	G	A	S	V	K	M	S	C	K	A	S	G	Y	T	F	T	S	Y	V	M	H	W	V	K	Q	K	P	G	Q	G	L	E	W	I	G	Y	I	N	P	Y	N	D	G	T	K	Y	N	E	K	F	K	G	K	A	T	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)														T	T											S	S		G	G	G	S									T	T	S										T	T	T	T						G	G	G	B	T	T	B
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	T	S	D	K	S	S	S	T	A	Y	M	E	L	S	S	L	T	S	E	D	S	A	V	Y	Y	C	A	R	G	A	Y	K	R	G	Y	A	M	D	Y	W	G	Q	G	T	S	V	T	V	S	S	D	L	V	M	S	Q	S	P	S	S	L	A	V	S	A	G	E	K	V	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				G	G	G	T								S			G	G	G											G	G	G	T	T																						S		S						T	T	S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	M	S	C	K	S	S	Q	S	L	F	N	S	R	T	R	K	N	Y	L	A	W	Y	Q	Q	K	P	G	Q	S	P	K	L	L	I	Y	W	A	S	T	R	E	S	G	V	P	D	R	F	T	G	S	G	S	G	T	D	F	T	L	T	I	S	S	V	Q	A	E	D	L	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						S	S					T	T	T	T											T	T	S								T	T	T				T	T			T	T							T	T							S	S			G	G	G
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.
Sequence	V	Y	Y	C	K	Q	S	Y	Y	H	M	Y	T	F	G	S	G	T	K	L	E	I	K	H	H
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)									T	T