PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c2f17A_

Fold library id	PDB Header	Molecule	Title
c2f17A_	PDB header: transferase	Chain: A: PDB Molecule: thiamin pyrophosphokinase 1;	PDBTitle: mouse thiamin pyrophosphokinase in a ternary complex with2 pyrithiamin pyrophosphate and amp at 2.5 angstrom

Links to external resources
Added to library: Tue Mar 16 14:03:15 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence H H S S G L V P R G S H M E H A F T P L E P L L P T G N L K Y C L V V L N Q P L D A R F R H L W K K A L L R A C A D G G A N H L Y D L T E G

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
S
T T G G G S S S
S S
T T
S T T
T T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence E R E S F L P E F V S G D F D S I R P E V K E Y Y T K K G C D L I S T P D Q D H T D F T K C L Q V L Q R K I E E K E L Q V D V I V T L G G L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
G G G S
S
S S S S
T T
T T S
T T
S
S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence G G R F D Q I M A S V N T L F Q A T H I T P V P I I I I Q K D S L I Y L L Q P G K H R L H V D T G M E G S W C G L I P V G Q P C N Q V T T T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S
G G G T
S S
T T
S
S S
S S

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . .

Sequence G L K W N L T N D V L G F G T L V S T S N T Y D G S G L V T V E T D H P L L W T M A I K S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S B S S
S S B T T T B
B
S S S S S

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

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Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	H	H	S	S	G	L	V	P	R	G	S	H	M	E	H	A	F	T	P	L	E	P	L	L	P	T	G	N	L	K	Y	C	L	V	V	L	N	Q	P	L	D	A	R	F	R	H	L	W	K	K	A	L	L	R	A	C	A	D	G	G	A	N	H	L	Y	D	L	T	E	G
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			S		S														T	T	G	G	G	S	S	S											S	S				T	T									S						T	T										T	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	E	R	E	S	F	L	P	E	F	V	S	G	D	F	D	S	I	R	P	E	V	K	E	Y	Y	T	K	K	G	C	D	L	I	S	T	P	D	Q	D	H	T	D	F	T	K	C	L	Q	V	L	Q	R	K	I	E	E	K	E	L	Q	V	D	V	I	V	T	L	G	G	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		G	G	G	S			S						S	S	S	S											T	T									T	T	S																	T	T				S								S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	G	G	R	F	D	Q	I	M	A	S	V	N	T	L	F	Q	A	T	H	I	T	P	V	P	I	I	I	I	Q	K	D	S	L	I	Y	L	L	Q	P	G	K	H	R	L	H	V	D	T	G	M	E	G	S	W	C	G	L	I	P	V	G	Q	P	C	N	Q	V	T	T	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S	S															G	G	G	T		S	S							T	T								S									S	S												S	S
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.
Sequence	G	L	K	W	N	L	T	N	D	V	L	G	F	G	T	L	V	S	T	S	N	T	Y	D	G	S	G	L	V	T	V	E	T	D	H	P	L	L	W	T	M	A	I	K	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S	B	S	S			S	S				B	T	T	T	B							B		S	S	S							S	S