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  Protein Homology/analogY Recognition Engine V 2.2
 

Fold library entry viewer: c2dtgE_

Fold library idPDB HeaderMoleculeTitle
c2dtgE_PDB header: hormone receptor/immune systemChain: E: PDB Molecule: insulin receptor;PDBTitle: insulin receptor (ir) ectodomain in complex with fab's


Added to library: Tue Mar 16 14:27:08 2010
 
Links to external resources


 1........10.........20.........30.........40.........50.........60.........70
Sequence PGEVCPGMDIRNNLTRLHELENCSVIEGHLQILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLK
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Known secondary structure (DSSP)


SSSGGGGGSSS


BSS

GGGTTT



S

SS

SBTT

B
 .........80.........90.........100.........110.........120.........130.........140
Sequence DLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDN
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Known secondary structure (DSSP)
TT



SS
BTTS
TT

B



S

B

S


S


BTSSS
SS

TT
 .........150.........160.........170.........180.........190.........200.........210
Sequence HIVLNKDDNEECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSECL
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Known secondary structure (DSSP) SSSTTSS





S
TT
SS

S

GGG


BSSSS
B




TTTGGG
B
SSS
B

TT

 .........220.........230.........240.........250.........260.........270.........280
Sequence GNCSQPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHHKCKNSRRQGCHQYVIHNNK
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Known secondary structure (DSSP) SSSSS
GGG

SS
BBTTB

SS

SS



TTSB


SS


STTTTS



TT
 .........290.........300.........310.........320.........330.........340.........350
Sequence CIPECPSGYTMNSSNLLCTPCLGPCPKVCHLLEGEKTIDSVTSAQELRGCTVINGSLIINIRGGNNLAAE
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Known secondary structure (DSSP) SS

SS

SSS
B


SS




TTS




STTTT

SS






SST
 .........360.........370.........380.........390.........400.........410.........420
Sequence LEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETLEIGNYSFYALDNQNLRQLWDWSKHNLTITQ
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Known secondary structure (DSSP) TT

SS
S
TT
SBGGGGTT



TT
BTTTS
TT

BS

TTS


B
SS
 .........430.........440.........450.........460.........470.........480.........490
Sequence GKLFFHYNPKLCLSEIHKMEEVSGTKGRQERNDIALKTNGDQASCENELLKFSYIRTSFDKILLRWEPYW
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Known secondary structure (DSSP)
SBTTS
TT
SSS

SSSB
STTBSTT


S

B


S
SS





 .........500.........510.........520.........530.........540.........550.........560
Sequence PPDFRDLLGFMLFYKEAPYQNVTEFDGQDACGSNSWTVVDIDPPLRSNDPKSQNHPGWLMRGLKPWTQYA
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Known secondary structure (DSSP) SSS





SSS

TTT








S








S





SSS


S

SS
B

 .........570.........580.........590.........600.........610.........620.........630
Sequence IFVKTLVTFSDERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWE
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Known secondary structure (DSSP) B




SS





B


B

B









SSS




SSSS
S

 .........640.........650.........660.........670.........680.........690.........700
Sequence RQAEDSELFELDYCLKGLKLPSEHRPFEKVVNKESLVISGLRHFTGYRIELQACNQDTPEERCSVAAYVS
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Known secondary structure (DSSP)



S
TT
SSS
S







S
S

S
S
SS
SS


S
SSSS

B




 .........710.........720.........730.........740.........750.........760.........770
Sequence ARTMPEAKADDIVGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLCDTRKHFALERGC
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SSSSS









S
SS




BSSSB







SSS


TT

 .........780.........790.........800.......
Sequence RLRGLSPGNYSVRIRATSLAGNGSWTEPTYFYVTDYL
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Known secondary structure (DSSP)


S

SS




TTB














Download:PDB structure FASTA sequence

Hidden Markov model

Image coloured by rainbow N → C terminus
Interactive 3D view in JSmol


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Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction
Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960
 
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