PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c2c1nA_

Fold library id	PDB Header	Molecule	Title
c2c1nA_	PDB header: signaling protein	Chain: A: PDB Molecule: 14-3-3 protein zeta/delta;	PDBTitle: molecular basis for the recognition of phosphorylated and2 phosphoacetylated histone h3 by 14-3-3

Links to external resources
Added to library: Tue Mar 16 13:14:47 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence M D K N E L V Q K A K L A E Q A E R Y D D M A A C M K S V T E Q G A E L S N E E R N L L S V A Y K N V V G A R R S S W R V V S S I E Q K T E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
T T
S
T T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence G A E K K Q Q M A R E Y R E K I E T E L R D I C N D V L S L L E K F L I P N A S Q A E S K V F Y L K M K G D Y Y R Y L A E V A K G I V D Q S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
T T T T T
S T T
T T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence Q Q A Y Q E A F E I S K K E M Q P T H P I R L G L A L N F S V F Y Y E I L N S P E K A C S L A K T A F D E A I A E L D T L S E E S Y K D S T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
T T
T S
T T G G G
T T T

. . . . . . . . . 220 . . . . .

Sequence L I M Q L L R D N L T L W T S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	M	D	K	N	E	L	V	Q	K	A	K	L	A	E	Q	A	E	R	Y	D	D	M	A	A	C	M	K	S	V	T	E	Q	G	A	E	L	S	N	E	E	R	N	L	L	S	V	A	Y	K	N	V	V	G	A	R	R	S	S	W	R	V	V	S	S	I	E	Q	K	T	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																T	T														T	T		S																																			T	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	G	A	E	K	K	Q	Q	M	A	R	E	Y	R	E	K	I	E	T	E	L	R	D	I	C	N	D	V	L	S	L	L	E	K	F	L	I	P	N	A	S	Q	A	E	S	K	V	F	Y	L	K	M	K	G	D	Y	Y	R	Y	L	A	E	V	A	K	G	I	V	D	Q	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T																																	T	T	T	T	T			S																				T	T			T	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	Q	Q	A	Y	Q	E	A	F	E	I	S	K	K	E	M	Q	P	T	H	P	I	R	L	G	L	A	L	N	F	S	V	F	Y	Y	E	I	L	N	S	P	E	K	A	C	S	L	A	K	T	A	F	D	E	A	I	A	E	L	D	T	L	S	E	E	S	Y	K	D	S	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)															S		T	T																		T	S																			T	T	G	G	G			T	T	T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.
Sequence	L	I	M	Q	L	L	R	D	N	L	T	L	W	T	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)													T	T