PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c1zvdA_

Fold library id	PDB Header	Molecule	Title
c1zvdA_	PDB header: ligase	Chain: A: PDB Molecule: smad ubiquitination regulatory factor 2;	PDBTitle: regulation of smurf2 ubiquitin ligase activity by anchoring2 the e2 to the hect domain

Links to external resources
Added to library: Tue Mar 16 13:56:41 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence K R D L V Q K L K I L R Q E L S Q Q Q P Q A G H C R I E V S R E E I F E E S Y R Q V X K X R P K D L W K R L X I K F R G E E G L D Y G G V A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S
S S
S T T T S
G G G G G S T T
S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence R E W L Y L L S H E X L N P Y Y G L F Q Y S R D D I Y T L Q I N P D S A V N P E H L S Y F H F V G R I X G X A V F H G H Y I D G G F T L P F

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T S G G G S S T T
T T G G G S T T T T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence Y K Q L L G K S I T L D D X E L V D P D L H N S L V W I L E N D I T G V L D H T F C V E H N A Y G E I I Q H E L K P N G K S I P V N E E N K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
S T T
S
T T T S
S T T S S T T
T T T T

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280

Sequence K E Y V R L Y V N W R F L R G I E A Q F L A L Q K G F N E V I P Q H L L K T F D E K E L E L I I C G L G K I D V N D W K V N T R L K H C T P

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T T S
G G G G T T
B S S
T S S
T

. . . . . . . . . 290 . . . . . . . . . 300 . . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350

Sequence D S N I V K W F W K A V E F F D E E R R A R L L Q F V T G S S R V P L Q G F K A L Q G A A G P R L F T I H Q I D A C T N N L P K A H T C F N

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T S S
S
S S B
T T
G G G
T T
T T S
G G G T

. . . . . . . . . 360 . . . . . . . . . 370 . . .

Sequence R I D I P P Y E S Y E K L Y E K L L T A I E E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S

Download: PDB structure FASTA sequence
Hidden Markov model

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	K	R	D	L	V	Q	K	L	K	I	L	R	Q	E	L	S	Q	Q	Q	P	Q	A	G	H	C	R	I	E	V	S	R	E	E	I	F	E	E	S	Y	R	Q	V	X	K	X	R	P	K	D	L	W	K	R	L	X	I	K	F	R	G	E	E	G	L	D	Y	G	G	V	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			S																S		S	S									S	T	T											T	S		G	G	G	G	G	S							T	T				S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	R	E	W	L	Y	L	L	S	H	E	X	L	N	P	Y	Y	G	L	F	Q	Y	S	R	D	D	I	Y	T	L	Q	I	N	P	D	S	A	V	N	P	E	H	L	S	Y	F	H	F	V	G	R	I	X	G	X	A	V	F	H	G	H	Y	I	D	G	G	F	T	L	P	F
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)												T	S	G	G	G	S	S					T	T									T	T	G	G	G	S	T	T																		T	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	Y	K	Q	L	L	G	K	S	I	T	L	D	D	X	E	L	V	D	P	D	L	H	N	S	L	V	W	I	L	E	N	D	I	T	G	V	L	D	H	T	F	C	V	E	H	N	A	Y	G	E	I	I	Q	H	E	L	K	P	N	G	K	S	I	P	V	N	E	E	N	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)					T	T					S	T	T																		S			T	T	T	S				S							T	T							S	S	T	T							T	T	T	T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Sequence	K	E	Y	V	R	L	Y	V	N	W	R	F	L	R	G	I	E	A	Q	F	L	A	L	Q	K	G	F	N	E	V	I	P	Q	H	L	L	K	T	F	D	E	K	E	L	E	L	I	I	C	G	L	G	K	I	D	V	N	D	W	K	V	N	T	R	L	K	H	C	T	P
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)													T	T	T	T															S		G	G	G	G	T	T													B	S	S									T					S	S		T
	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
Sequence	D	S	N	I	V	K	W	F	W	K	A	V	E	F	F	D	E	E	R	R	A	R	L	L	Q	F	V	T	G	S	S	R	V	P	L	Q	G	F	K	A	L	Q	G	A	A	G	P	R	L	F	T	I	H	Q	I	D	A	C	T	N	N	L	P	K	A	H	T	C	F	N
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	S													S														S		S	S	B		T	T		G	G	G				T	T														T	T	S						G	G	G	T
	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.
Sequence	R	I	D	I	P	P	Y	E	S	Y	E	K	L	Y	E	K	L	L	T	A	I	E	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)								S	S