PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c1y1yE_

Fold library id	PDB Header	Molecule	Title
c1y1yE_	PDB header: transferase/transcription/dna-rna hybrid	Chain: E: PDB Molecule: dna-directed rna polymerases i, ii, and iii 27	PDBTitle: rna polymerase ii-tfiis-dna/rna complex

Links to external resources
Added to library: Tue Mar 16 12:15:20 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence D Q E N E R N I S R L W R A F R T V K E M V K D R G Y F I T Q E E V E L P L E D F K A K Y C D S M G R P Q R K M M S F Q A N P T E E S I S K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T T
T T T S S
T T
T T S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence F P D M G S L W V E F C D E P S V G V K T M K T F V I H I Q E K N F Q T G I F V Y Q N N I T P S A M K L V P S I P P A T I E T F N E A A L V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S
S
S S B
T T T
S S S
B
T T T G G G G G G S
S S T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence V N I T H H E L V P K H I R L S S D E K R E L L K R Y R L K E S Q L P R I Q R A D P V A L Y L G L K R G E V V K I I R K S E T S G R Y A S Y

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
G G G S T T
B
T
S T T S
S S
T T
T T
S S S S

. . . .

Sequence R I C M

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	D	Q	E	N	E	R	N	I	S	R	L	W	R	A	F	R	T	V	K	E	M	V	K	D	R	G	Y	F	I	T	Q	E	E	V	E	L	P	L	E	D	F	K	A	K	Y	C	D	S	M	G	R	P	Q	R	K	M	M	S	F	Q	A	N	P	T	E	E	S	I	S	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			T																						T	T					T	T	T	S	S									T	T			T	T	S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	F	P	D	M	G	S	L	W	V	E	F	C	D	E	P	S	V	G	V	K	T	M	K	T	F	V	I	H	I	Q	E	K	N	F	Q	T	G	I	F	V	Y	Q	N	N	I	T	P	S	A	M	K	L	V	P	S	I	P	P	A	T	I	E	T	F	N	E	A	A	L	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		S	S										S		S	S	B		T	T													T		S							S	S		B		T	T	T	G	G	G	G	G	G	S		S	S											T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	V	N	I	T	H	H	E	L	V	P	K	H	I	R	L	S	S	D	E	K	R	E	L	L	K	R	Y	R	L	K	E	S	Q	L	P	R	I	Q	R	A	D	P	V	A	L	Y	L	G	L	K	R	G	E	V	V	K	I	I	R	K	S	E	T	S	G	R	Y	A	S	Y
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S		G	G	G	S	T	T						B														T			S	T	T	S					S	S							T	T			T	T										S	S	S	S
	.	.	.	.
Sequence	R	I	C	M
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)